Immunohistochemical analysis of c-erbB-2, Bcl-2, p53, p21
Adolescent
Adult
Biomarkers, Tumor
/ analysis
Cyclin-Dependent Kinase Inhibitor p21
/ analysis
Female
Humans
Hydatidiform Mole
/ metabolism
Immunohistochemistry
Ki-67 Antigen
/ analysis
Membrane Proteins
/ analysis
Middle Aged
Pregnancy
Proto-Oncogene Proteins c-bcl-2
/ analysis
Receptor, ErbB-2
/ analysis
Retrospective Studies
Tumor Suppressor Protein p53
/ analysis
Uterine Neoplasms
/ metabolism
Young Adult
Bcl-2
Complete hydatidiform mole
Hydropic abortion
Ki-67
Partial hydatidiform mole
p53
p63
Journal
Pathology, research and practice
ISSN: 1618-0631
Titre abrégé: Pathol Res Pract
Pays: Germany
ID NLM: 7806109
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
23
09
2018
revised:
23
11
2018
accepted:
11
12
2018
pubmed:
19
12
2018
medline:
11
4
2019
entrez:
19
12
2018
Statut:
ppublish
Résumé
Hydatidiform moles (HM) are characterized by an abnormal proliferating trophoblast with a potential for a malignant transformation. Similar to other human tumors, trophoblastic pathogenesis is likely a multistep process involving several molecular and genetic alterations. The study was performed to investigate the expression patterns of c-erbB-2 and Bcl-2 oncoproteins, p53, p21
Identifiants
pubmed: 30558966
pii: S0344-0338(18)31281-0
doi: 10.1016/j.prp.2018.12.015
pii:
doi:
Substances chimiques
BCL2 protein, human
0
Biomarkers, Tumor
0
CDKN1A protein, human
0
CKAP4 protein, human
0
Cyclin-Dependent Kinase Inhibitor p21
0
Ki-67 Antigen
0
Membrane Proteins
0
Proto-Oncogene Proteins c-bcl-2
0
TP53 protein, human
0
Tumor Suppressor Protein p53
0
ERBB2 protein, human
EC 2.7.10.1
Receptor, ErbB-2
EC 2.7.10.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
446-452Informations de copyright
Copyright © 2018 Elsevier GmbH. All rights reserved.