Field Performance of PIMA Point-of-Care Machine for CD4 Enumeration Under a Mobile HIV Counseling and Testing Program in Remote Fishing Communities of Lake Victoria, Uganda.
CD4 count
FACSCount
HIV
point of care
Journal
AIDS research and human retroviruses
ISSN: 1931-8405
Titre abrégé: AIDS Res Hum Retroviruses
Pays: United States
ID NLM: 8709376
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
pubmed:
19
12
2018
medline:
15
4
2020
entrez:
19
12
2018
Statut:
ppublish
Résumé
Uganda is among the most HIV/AIDS-afflicted countries, and many HIV-infected persons live in remote areas with poor access to health care. The success of HIV care programs relies in part on patient monitoring using CD4 T cell counts. We conducted an evaluation of the point-of-care PIMA test using BD FACSCount as a gold standard. One hundred fifty-one participants were enrolled, provided venous blood and samples tested at the point of care with the Alere PIMA™ CD4 Analyzer and the BD FACSCount in the UVRI-IAVI main laboratory. Correlation between the methods was assessed, as was the ability of the Pima Analyzer to predict values <200, <350, and ≥500 CD4 cells/mm
Identifiants
pubmed: 30560683
doi: 10.1089/AID.2018.0223
pmc: PMC6461303
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
382-387Subventions
Organisme : FIC NIH HHS
ID : D43 TW010132
Pays : United States
Organisme : Wellcome Trust
ID : 107743/Z/15/Z
Pays : United Kingdom
Références
Pan Afr Med J. 2015 Jun 09;21:104
pubmed: 26379811
Int J STD AIDS. 2014 Nov;25(13):956-9
pubmed: 24616116
Lancet. 1985 Oct 19;2(8460):849-52
pubmed: 2864575
PLoS One. 2013 Aug 05;8(8):e70770
pubmed: 23940638
Sex Transm Infect. 2011 Oct;87(6):511-5
pubmed: 21835763
PLoS One. 2013 Sep 16;8(9):e75484
pubmed: 24066184
Chin Med J (Engl). 2015 Apr 5;128(7):890-5
pubmed: 25836608
Sex Transm Dis. 2012 Jun;39(6):433-9
pubmed: 22592828
PLoS One. 2013 Jun 25;8(6):e67612
pubmed: 23825674
PLoS Med. 2012;9(3):e1001194
pubmed: 22448150
BMC Infect Dis. 2016 Oct 21;16(1):592
pubmed: 27769181
PLoS One. 2015 Nov 24;10(11):e0143988
pubmed: 26599276
J Int AIDS Soc. 2013 Jul 22;16:18621
pubmed: 23880102
Lancet. 1986 Feb 8;1(8476):307-10
pubmed: 2868172
J Immunol Methods. 2017 Sep;448:44-50
pubmed: 28529048
BMC Med. 2015 Jul 25;13:168
pubmed: 26208867
Clin Infect Dis. 2010 Aug 15;51(4):448-55
pubmed: 20597693
PLoS One. 2014 Mar 10;9(3):e88928
pubmed: 24614083
Sex Transm Infect. 2016 Sep;92(6):447-54
pubmed: 26933046
PLoS One. 2017 Feb 16;12(2):e0171200
pubmed: 28207844