Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle.

Amino Acid Sequence Animals Dose-Response Relationship, Drug Follistatin / administration & dosage Humans Immunoglobulin G / administration & dosage Injections, Intramuscular Male Mice Mice, Inbred C57BL Muscle, Skeletal / drug effects Protein Structure, Secondary Recombinant Fusion Proteins / administration & dosage

Journal

The Journal of pharmacology and experimental therapeutics
ISSN: 1521-0103
Titre abrégé: J Pharmacol Exp Ther
Pays: United States
ID NLM: 0376362

Informations de publication

Date de publication:
03 2019
Historique:
received: 30 07 2018
accepted: 06 12 2018
pubmed: 20 12 2018
medline: 2 11 2019
entrez: 20 12 2018
Statut: ppublish

Résumé

Follistatin is an endogenous glycoprotein that promotes growth and repair of skeletal muscle by sequestering inhibitory ligands of the transforming growth factor-

Identifiants

DOI: 10.1124/jpet.118.252304 PMID: 30563942
pubmed: 30563942
pii: jpet.118.252304
doi: 10.1124/jpet.118.252304
doi:

Substances chimiques

Follistatin 0
Immunoglobulin G 0
Recombinant Fusion Proteins 0
follistatin, 288-amino acid isoform 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

435-445

Informations de copyright

Copyright © 2019 The Author(s).

Auteurs

Roselyne Castonguay (R)

Acceleron Pharma, Cambridge, Massachusetts rcastonguay@acceleronpharma.com.

Jennifer Lachey (J)

Acceleron Pharma, Cambridge, Massachusetts.

Samantha Wallner (S)

Acceleron Pharma, Cambridge, Massachusetts.

Jamie Strand (J)

Acceleron Pharma, Cambridge, Massachusetts.

Katia Liharska (K)

Acceleron Pharma, Cambridge, Massachusetts.

Abigail E Watanabe (AE)

Acceleron Pharma, Cambridge, Massachusetts.

Marishka Cannell (M)

Acceleron Pharma, Cambridge, Massachusetts.

Monique V Davies (MV)

Acceleron Pharma, Cambridge, Massachusetts.

Dianne Sako (D)

Acceleron Pharma, Cambridge, Massachusetts.

Megan E Troy (ME)

Acceleron Pharma, Cambridge, Massachusetts.

Lavanya Krishnan (L)

Acceleron Pharma, Cambridge, Massachusetts.

Aaron W Mulivor (AW)

Acceleron Pharma, Cambridge, Massachusetts.

Huiming Li (H)

Acceleron Pharma, Cambridge, Massachusetts.

Sarah Keates (S)

Acceleron Pharma, Cambridge, Massachusetts.

Mark J Alexander (MJ)

Acceleron Pharma, Cambridge, Massachusetts.

R Scott Pearsall (RS)

Acceleron Pharma, Cambridge, Massachusetts.

Ravi Kumar (R)

Acceleron Pharma, Cambridge, Massachusetts.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Eucaryotes › Animaux › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Follistatine › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline G › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Voies d'administration de substances chimiques et des médicaments › Injections › Injections musculaires › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Muscles squelettiques › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Follistatin-288-Fc Fusion Protein Promotes...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines recombinantes › Protéines de fusion recombinantes › Follistatin-288-Fc Fusion Protein Promotes...