Toxic doses of caffeine are needed to increase skeletal muscle contractility.

Adult Animals Caffeine / administration & dosage Dose-Response Relationship, Drug Electromyography / drug effects Female Humans Male Mice Mice, Inbred C57BL Muscle Contraction / drug effects Muscle, Skeletal / drug effects Organ Culture Techniques Young Adult
contractile properties electrical stimulation intact single fiber intracellular Ca muscle force

Journal

American journal of physiology. Cell physiology
ISSN: 1522-1563
Titre abrégé: Am J Physiol Cell Physiol
Pays: United States
ID NLM: 100901225

Informations de publication

Date de publication:
01 02 2019
Historique:
pubmed: 20 12 2018
medline: 15 11 2019
entrez: 20 12 2018
Statut: ppublish

Résumé

Discrepant results have been reported regarding an intramuscular mechanism underlying the ergogenic effect of caffeine on neuromuscular function in humans. Here, we reevaluated the effect of caffeine on muscular force production in humans and combined this with measurements of the caffeine dose-response relationship on force and cytosolic free [Ca

Identifiants

DOI: 10.1152/ajpcell.00269.2018 PMID: 30566390
pubmed: 30566390
doi: 10.1152/ajpcell.00269.2018
doi:

Substances chimiques

Caffeine 3G6A5W338E

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

C246-C251

Auteurs

Daria Neyroud (D)

Institute of Sport Sciences, University of Lausanne , Lausanne , Switzerland.
ORCID: 0000-0001-5886-802X

Arthur J Cheng (AJ)

Department of Physiology and Pharmacology, Karolinska Institutet , Stockholm , Sweden.
ORCID: 0000-0003-3862-2967

Chris Donnelly (C)

Institute of Sport Sciences, University of Lausanne , Lausanne , Switzerland.

Nicolas Bourdillon (N)

Institute of Sport Sciences, University of Lausanne , Lausanne , Switzerland.

Anne-Laure Gassner (AL)

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Lausanne, Switzerland.

Laurent Geiser (L)

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Lausanne, Switzerland.

Serge Rudaz (S)

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Lausanne, Switzerland.

Bengt Kayser (B)

Institute of Sport Sciences, University of Lausanne , Lausanne , Switzerland.
ORCID: 0000-0002-9776-7501

Håkan Westerblad (H)

Department of Physiology and Pharmacology, Karolinska Institutet , Stockholm , Sweden.
ORCID: 0000-0002-8180-3029

Nicolas Place (N)

Institute of Sport Sciences, University of Lausanne , Lausanne , Switzerland.
ORCID: 0000-0001-9044-0621

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Eucaryotes › Animaux › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Xanthines › Caféine › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Myographie › Électromyographie › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Contraction musculaire › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Muscles squelettiques › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture d'organes › Toxic doses of caffeine are needed to increase...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Toxic doses of caffeine are needed to increase...