Sex-specific relationship between adult height and the risk of stroke: A dose-response meta-analysis of prospective studies.
adult height
meta-analysis
prospective studies
sex difference
stroke
Journal
Journal of clinical hypertension (Greenwich, Conn.)
ISSN: 1751-7176
Titre abrégé: J Clin Hypertens (Greenwich)
Pays: United States
ID NLM: 100888554
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
04
09
2018
revised:
08
10
2018
accepted:
30
10
2018
pubmed:
21
12
2018
medline:
17
6
2020
entrez:
21
12
2018
Statut:
ppublish
Résumé
Conflicting evidence exists regarding the magnitude of the association between adult height and risk of stroke, and it is unclear whether this association is different between men and women. The authors carried out a meta-analysis to assess the sex-specific effect of adult height on the risk of stroke and its subtypes. Prospective cohort studies reporting sex-specific risk estimates of height with stroke or reported in a certain sex were included. Summary relative risks for 5-unit increments in height were calculated using random-effects, and dose-response relationships were performed using a restricted cubic spline model. Subgroup analyses, sensitivity analyses, and tests for publication bias were also performed. In all, 20 prospective studies were identified in this study. The summary of relative risks (95% CIs) of stroke for a 5 cm increase in adult height were 0.93 (0.90-0.95) for men and 0.88 (0.83-0.93) for women. There was no significant difference in the effect of height on future stroke risk between men and women (P
Identifiants
pubmed: 30570201
doi: 10.1111/jch.13458
pmc: PMC8030415
doi:
Types de publication
Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
262-270Informations de copyright
©2018 Wiley Periodicals, Inc.
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