Dimeric 2-(2-phenylethyl)chromones from the agarwood of Aquilaria crassna in Laos.

Cell Line, Tumor Flavonoids / chemistry Humans Laos Molecular Structure Phytochemicals / chemistry Thymelaeaceae / chemistry Wood / chemistry
Agarwood Aquilaria crassna Cytotoxicity Dimeric 2-(2-phenylethyl)chromone

Journal

Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 07 09 2018
revised: 11 12 2018
accepted: 16 12 2018
pubmed: 21 12 2018
medline: 26 3 2019
entrez: 21 12 2018
Statut: ppublish

Résumé

Four new dimeric 2-(2-phenylethyl)chromones (1-4) were isolated from the agarwood of Aquilaria crassna in Laos. All structures were determined based on extensive spectroscopic methods including IR, UV, 1D and 2D NMR, ECD, and HRMS. The structures of compounds 1-3 were characterized by two C-O-C linkages between the two chromone moieties, while compound 4 featured one C-O-C linkage and one CC bond connecting with two chromone moieties. Compounds 1 and 3 showed weak cytotoxicity against human hepatocellular carcinoma BEL-7402 cell line with IC

Identifiants

DOI: 10.1016/j.fitote.2018.12.006 PMID: 30572084
pubmed: 30572084
pii: S0367-326X(18)31074-8
doi: 10.1016/j.fitote.2018.12.006
pii:
doi:

Substances chimiques

Flavonoids 0
Phytochemicals 0
2-(2-phenylethyl)chromone 61828-53-3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12-16

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Wei Li (W)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China.

Yang Yang (Y)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Wenhua Dong (W)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China.

Hao Wang (H)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China.

Fandong Kong (F)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China.

Caihong Cai (C)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China.

Wenli Mei (W)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China. Electronic address: meiwenli@itbb.org.cn.

Haofu Dai (H)

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Hainan Engineering Research Center of Agarwood, Haikou 571101, China. Electronic address: daihaofu@itbb.org.cn.

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Classifications MeSH

questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Régions géographiques › Asie › Asie du Sud-Est › Laos › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Thymelaeaceae › Dimeric 2-(2-phenylethyl)chromones from the...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux de construction › Bois › Dimeric 2-(2-phenylethyl)chromones from the...