Manganese levels in newborns' hair by maternal sociodemographic, dietary and environmental factors.
Hair analysis
In utero exposure
Manganese
PM2.5
Smoking
Journal
Environmental research
ISSN: 1096-0953
Titre abrégé: Environ Res
Pays: Netherlands
ID NLM: 0147621
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
17
07
2018
revised:
21
11
2018
accepted:
22
11
2018
pubmed:
24
12
2018
medline:
18
12
2019
entrez:
22
12
2018
Statut:
ppublish
Résumé
Exposure to manganese (Mn) has been associated with neurodevelopmental problems in children. Mn exposure begins in utero, and maternal sociodemographic, dietary and environmental factors may affect Mn levels in newborns' hair. This study aimed to characterize in utero Mn exposure using Mn levels in newborns' hair as a biomarker of prenatal exposure, and to analyze its relationship with sociodemographic, dietary and environmental factors in the Spanish INMA-Gipuzkoa cohort. Overall, 638 pregnant women were recruited in the first trimester of pregnancy and a hair sample was obtained from 473 newborns. Sociodemographic, dietary and environmental data were recorded through two questionnaires administered in the first and third trimesters of pregnancy. The median Mn concentration in newborns´ hair was 0.31 µg/g (P5 = 0.02; P95 = 1.23). Mn levels in newborns´ hair were associated with smoking during pregnancy (β = 0.222; 95% CI = 0.065-0.379) and with maternal PM
Identifiants
pubmed: 30576994
pii: S0013-9351(18)30621-2
doi: 10.1016/j.envres.2018.11.038
pii:
doi:
Substances chimiques
Manganese
42Z2K6ZL8P
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
92-100Informations de copyright
Copyright © 2018. Published by Elsevier Inc.