Cytomegalovirus shedding from breastmilk and mucosal sites in healthy postpartum women: A pilot study.
breastmilk
cytomegalovirus
postpartum
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
05
07
2018
accepted:
20
12
2018
pubmed:
24
12
2018
medline:
18
3
2020
entrez:
23
12
2018
Statut:
ppublish
Résumé
Mother-to-child cytomegalovirus (CMV) breastmilk transmission can occur in the postnatal period. In a pilot study, we measured daily CMV detection by polymerase chain reaction in breastmilk, vaginal, and saliva samples from nine healthy CMV-seropositive postpartum women for 28 days. CMV was found in seven of nine women and 171 of 253 breastmilk samples (67.6%). In four women, all breastmilk samples were positive. CMV was less frequently detected in the vagina (39 of 258, 15.1%) and saliva (53 of 258, 20.5%). Daily breastmilk, oral, and genital collection is feasible and demonstrates high variability between women. Further study of the dynamics of CMV in distinct anatomic compartments is warranted.
Identifiants
pubmed: 30578684
doi: 10.1002/jmv.25386
pmc: PMC6402967
mid: NIHMS1003955
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
894-898Subventions
Organisme : NIAID NIH HHS
ID : P01 AI030731
Pays : United States
Organisme : NIAID NIH HHS
ID : K24 AI071113
Pays : United States
Informations de copyright
© 2018 Wiley Periodicals, Inc.
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