Testicular Fine-Needle Aspiration for Sperm Retrieval in Azoospermia: A Small Step toward the Technical Standardization.
Azoospermia
Biopsy, fine-needle
Infertility, male
Reproductive techniques
Sperm retrieval
Journal
The world journal of men's health
ISSN: 2287-4208
Titre abrégé: World J Mens Health
Pays: Korea (South)
ID NLM: 101596899
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
31
08
2018
revised:
23
10
2018
accepted:
24
10
2018
entrez:
26
12
2018
pubmed:
26
12
2018
medline:
26
12
2018
Statut:
ppublish
Résumé
The aim was to describe our preliminary experience performing testicular fine-needle aspiration (TEFNA) with a larger needle in infertile patients with obstructive azoospermia, and to provide a systematic literature review of the different testicular sperm aspiration techniques, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We prospectively collected data between March 2017 and June 2018. All men underwent bilateral TEFNA under analgo-sedation, using a larger disposable 18-gauge butterfly needle with 60 mL Luer-Lock syringe attached to it. Thirty consecutive patients were enrolled. Median operative time was 16 minutes (interquartile range [IQR]: 12-30 minutes). No intraoperative complications occurred. Two/thirty patients (6.7%) reported postoperative adverse events: 1 patient had prolonged orchialgia, 1 patient presented scrotal hematoma. Successful sperm retrieval was found in 28/30 cases (93.3%). Median sperm concentration was 0.05 ×10⁶/mL (IQR: 0.001-0.1 ×10⁶/mL). Median total sperm motility was 10% (IQR: 0%-15%). In 20/30 men (66.7%) sperm retrieved was used for fresh intracytoplasmic sperm injection cycle, in 8/30 (26.7%) sperm cryopreservation was necessary, because on the day of sperm retrieval the female resulted not responder to ovarian stimulation. In this cases mean number of 3 (IQR: 1-4) bio system straws was cryopreserved. TEFNA with 18-gauge needle proved to be a feasible, safe and effective treatment, even if future prospective studies will be addressed to clarify what type of azoospermia benefits from this procedure, and if a larger needle permits to improve Assisted Reproductive Technologies (ART) outcomes.
Identifiants
pubmed: 30584991
pii: 37.55
doi: 10.5534/wjmh.180077
pmc: PMC6305866
doi:
Types de publication
Journal Article
Langues
eng
Pagination
55-67Informations de copyright
Copyright © 2019 Korean Society for Sexual Medicine and Andrology.
Déclaration de conflit d'intérêts
The authors have no potential conflicts of interest to disclose.
Références
Urology. 1999 Mar;53(3):604-7
pubmed: 10096391
Fertil Steril. 1999 Apr;71(4):756-60
pubmed: 10202893
Hum Reprod. 1999 Jan;14(1):118-22
pubmed: 10374107
Hum Reprod. 1999 Jul;14(7):1785-90
pubmed: 10402390
Curr Opin Urol. 2000 Nov;10(6):617-24
pubmed: 11148736
Fertil Steril. 2001 Feb;75(2):423-8
pubmed: 11172851
Arch Androl. 2001 May-Jun;46(3):211-5
pubmed: 11339647
J Assist Reprod Genet. 2001 Mar;18(3):171-7
pubmed: 11411434
J Clin Ultrasound. 2001 Jul-Aug;29(6):339-43
pubmed: 11424099
Urol Int. 2002;68(2):86-90
pubmed: 11834896
J Urol. 2003 Feb;169(2):603-5
pubmed: 12544317
Urology. 2003 Aug;62(2):328-32
pubmed: 12893345
Reprod Biomed Online. 2004 Jul;9(1):102-5
pubmed: 15257830
Fertil Steril. 1992 Apr;57(4):858-65
pubmed: 1555700
Fertil Steril. 2005 Mar;83(3):606-11
pubmed: 15749488
J Androl. 2006 Jan-Feb;27(1):28-33
pubmed: 16400074
Urology. 1992 Feb;39(2):173-6
pubmed: 1736514
Histopathology. 2007 Aug;51(2):249-57
pubmed: 17650219
Int J Androl. 2008 Dec;31(6):595-601
pubmed: 17822417
Ann Surg. 1930 Aug;92(2):169-81
pubmed: 17866350
Hum Reprod Update. 2007 Nov-Dec;13(6):539-49
pubmed: 17895238
Reprod Biomed Online. 2008 Jan;16(1):89-95
pubmed: 18252053
Hormones (Athens). 2008 Apr-Jun;7(2):140-7
pubmed: 18477551
Acta Obstet Gynecol Scand. 2008;87(10):1033-8
pubmed: 18850334
J Urol. 2008 Dec;180(6):2577-80
pubmed: 18950806
Reprod Biomed Online. 2009 Apr;18(4):460-4
pubmed: 19400985
Urology. 2010 Jan;75(1):87-91
pubmed: 19931128
Aging Male. 2010 Mar;13(1):44-50
pubmed: 20121463
Indian J Urol. 2012 Jan;28(1):37-42
pubmed: 22557715
Clinics (Sao Paulo). 2013;68 Suppl 1:99-110
pubmed: 23503959
J Reprod Infertil. 2013 Apr;14(2):73-8
pubmed: 23926568
J Urol. 1989 Jul;142(1):62-5
pubmed: 2499695
Urology. 2014 Dec;84(6):1342-6
pubmed: 25432825
Andrologia. 2016 Apr;48(3):252-6
pubmed: 25998234
Andrology. 2016 Mar;4(2):257-62
pubmed: 26789006
Med Sci Monit. 2018 Mar 07;24:1379-1386
pubmed: 29511156
Urology. 1984 Nov;24(5):439-42
pubmed: 6495452
Hum Reprod. 1995 Oct;10(10):2595-9
pubmed: 8567777
Fertil Steril. 1997 Mar;67(3):527-35
pubmed: 9091342
Urology. 1997 May;49(5):743-8
pubmed: 9145981
Hum Reprod. 1997 Jul;12(7):1488-93
pubmed: 9262283
Hum Reprod. 1997 Aug;12(8):1688-92
pubmed: 9308794
Hum Reprod. 1998 Apr;13(4):901-4
pubmed: 9619545
Hum Reprod. 1998 May;13(5):1266-71
pubmed: 9647558
J Urol. 1998 Feb;159(2):437-40
pubmed: 9649258
Int J Androl. 1998 Oct;21(5):295-300
pubmed: 9805246
J Urol. 1998 Dec;160(6 Pt 1):2058-62
pubmed: 9817323
Hum Reprod. 1998 Nov;13(11):3075-80
pubmed: 9853859
Hum Reprod. 1998 Nov;13(11):3086-9
pubmed: 9853861
Hum Reprod. 1998 Dec;13(12):3390-3
pubmed: 9886520