Type and Duration of Exercise in the SAMMPRIS Trial.


Journal

The neurologist
ISSN: 2331-2637
Titre abrégé: Neurologist
Pays: United States
ID NLM: 9503763

Informations de publication

Date de publication:
Jan 2019
Historique:
entrez: 27 12 2018
pubmed: 27 12 2018
medline: 31 1 2019
Statut: ppublish

Résumé

Analyses from the Stenting and Aggressive Medical management for prevention of Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial showed that good control of vascular risk factors (systolic blood pressure, low-density lipoprotein, and exercise) was associated with fewer vascular events and exercise had the biggest impact on the outcome. We sought to determine the type and duration of exercise performed by SAMMPRIS patients during the trial. SAMMPRIS aggressive medical management included a telephonic lifestyle modification program, INTERVENT, that was provided free of charge to all subjects during the study. We analyzed self-reported data collected by INTERVENT on the patients' type and duration of exercise from baseline (n=394) to 3 years (n=132). We calculated the mean duration for each exercise type at each time period and then compared the change in exercise duration from baseline using paired t tests and Wilcoxon signed-rank tests. Walking was the most common form of exercise at all time points, as measured by both the duration of exercise and the number of patients performing the exercise. The mean duration of walking and other aerobic activities increased significantly from baseline to all other time points. The type of self-reported exercise performed by SAMMPRIS patients included mostly walking or other aerobic activity and increased significantly during follow-up.

Sections du résumé

BACKGROUND BACKGROUND
Analyses from the Stenting and Aggressive Medical management for prevention of Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial showed that good control of vascular risk factors (systolic blood pressure, low-density lipoprotein, and exercise) was associated with fewer vascular events and exercise had the biggest impact on the outcome. We sought to determine the type and duration of exercise performed by SAMMPRIS patients during the trial.
METHODS METHODS
SAMMPRIS aggressive medical management included a telephonic lifestyle modification program, INTERVENT, that was provided free of charge to all subjects during the study. We analyzed self-reported data collected by INTERVENT on the patients' type and duration of exercise from baseline (n=394) to 3 years (n=132). We calculated the mean duration for each exercise type at each time period and then compared the change in exercise duration from baseline using paired t tests and Wilcoxon signed-rank tests.
RESULTS RESULTS
Walking was the most common form of exercise at all time points, as measured by both the duration of exercise and the number of patients performing the exercise. The mean duration of walking and other aerobic activities increased significantly from baseline to all other time points.
CONCLUSIONS CONCLUSIONS
The type of self-reported exercise performed by SAMMPRIS patients included mostly walking or other aerobic activity and increased significantly during follow-up.

Identifiants

pubmed: 30586027
doi: 10.1097/NRL.0000000000000211
pii: 00127893-201901000-00003
pmc: PMC6310066
mid: NIHMS1505815
doi:

Substances chimiques

Fibrinolytic Agents 0

Types de publication

Clinical Trial, Phase III Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

10-12

Subventions

Organisme : NINDS NIH HHS
ID : K24 NS050307
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS058728
Pays : United States

Références

N Engl J Med. 2005 Mar 31;352(13):1305-16
pubmed: 15800226
Neurology. 2006 Apr 25;66(8):1187-91
pubmed: 16636236
Stroke. 2008 Aug;39(8):2396-9
pubmed: 18535283
Gerontology. 2009;55(1):64-72
pubmed: 18566534
Arch Phys Med Rehabil. 2010 Feb;91(2):288-97
pubmed: 20159136
J Stroke Cerebrovasc Dis. 2011 Jul-Aug;20(4):357-68
pubmed: 21729789
N Engl J Med. 2011 Sep 15;365(11):993-1003
pubmed: 21899409
Circ Cardiovasc Qual Outcomes. 2012 Sep 1;5(5):e51-60
pubmed: 22991350
Lancet. 2014 Jan 25;383(9914):333-41
pubmed: 24168957
Stroke. 2014 Aug;45(8):2532-53
pubmed: 24846875
Neurology. 2017 Jan 24;88(4):379-385
pubmed: 28003500
J Stroke Cerebrovasc Dis. 2018 Mar;27(3):801-805
pubmed: 29169967

Auteurs

Tanya N Turan (TN)

Department of Neurology, Medical University of South Carolina, Charleston, SC.

Sami Al Kasab (SA)

Departments of Neurology.

Azhar Nizam (A)

Department of public health, Emory University, Atlanta, GA.

Jessica Hannah (J)

Department of Neurology, Centura Health Physician Group Southwest, Durango, CO.

Neil Gordon (N)

INTERVENT International, LLC, Savannah, GA.

Michael J Lynn (MJ)

Department of public health, Emory University, Atlanta, GA.

Colin P Derdeyn (CP)

Radiology, University of Iowa, Iowa City, IA.

David Fiorella (D)

Department of Neurosurgery, State University of New York at Stony Brook, Stony Brook, NY.

L Scott Janis (LS)

Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD.

Bethany F Lane (BF)

Department of public health, Emory University, Atlanta, GA.

Jean Montgomery (J)

Department of public health, Emory University, Atlanta, GA.

Marc I Chimowitz (MI)

Department of Neurology, Medical University of South Carolina, Charleston, SC.

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Classifications MeSH