Comparative Assessment of CPET


Journal

In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809

Informations de publication

Date de publication:
Historique:
received: 28 09 2018
revised: 23 10 2018
accepted: 26 10 2018
entrez: 28 12 2018
pubmed: 28 12 2018
medline: 6 4 2019
Statut: ppublish

Résumé

Prevalence of chronic obstructive pulmonary disease (COPD) is increasing in Germany. This study examined the work performance of healthy women compared to those with mild COPD. Nineteen women suffering from COPD Global Initiative for Chronic Obstructive Lung Diseases stage I and 41 healthy women underwent standardised cardiopulmonary exercise test (CPET) in comparison to 5 typical work-related tasks. Oxygen uptake, carbon dioxide output, ventilation volume, breathing frequency, heart rate and respiratory exchange ratio (RER) were measured. The activities were quantified. Wilcoxon test and ANOVA were calculated using the SPSS software. Patients with COPD had a lower exercise capacity compared to healthy women and also showed lower performance during work-related activities. Patients with COPD had a lower oxygen uptake (p<0.001), a higher breathing frequency was accompanied by a higher Borg scale. The heart rate and the ventilation volume as a percentage of maximum CPET were significantly higher in patients with COPD. Women suffering from progressive symptoms had lower oxygen uptakes and RER, whilst breathing frequency and Borg scale were elevated. Even at an early stage of the disease, patients with COPD exhibited limitations in work-related tasks.

Sections du résumé

BACKGROUND BACKGROUND
Prevalence of chronic obstructive pulmonary disease (COPD) is increasing in Germany. This study examined the work performance of healthy women compared to those with mild COPD.
PATIENTS AND METHODS METHODS
Nineteen women suffering from COPD Global Initiative for Chronic Obstructive Lung Diseases stage I and 41 healthy women underwent standardised cardiopulmonary exercise test (CPET) in comparison to 5 typical work-related tasks. Oxygen uptake, carbon dioxide output, ventilation volume, breathing frequency, heart rate and respiratory exchange ratio (RER) were measured. The activities were quantified. Wilcoxon test and ANOVA were calculated using the SPSS software.
RESULTS RESULTS
Patients with COPD had a lower exercise capacity compared to healthy women and also showed lower performance during work-related activities. Patients with COPD had a lower oxygen uptake (p<0.001), a higher breathing frequency was accompanied by a higher Borg scale. The heart rate and the ventilation volume as a percentage of maximum CPET were significantly higher in patients with COPD. Women suffering from progressive symptoms had lower oxygen uptakes and RER, whilst breathing frequency and Borg scale were elevated.
CONCLUSION CONCLUSIONS
Even at an early stage of the disease, patients with COPD exhibited limitations in work-related tasks.

Identifiants

pubmed: 30587611
pii: 33/1/115
doi: 10.21873/invivo.11447
pmc: PMC6364052
doi:

Substances chimiques

Carbon Dioxide 142M471B3J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115-124

Informations de copyright

Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

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Auteurs

Joachim Schneider (J)

Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital, Giessen, Germany Joachim.Schneider@arbmed.med.uni-giessen.de.

Ines Lee Giesser (I)

Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital, Giessen, Germany.

Sandra Laux (S)

Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital, Giessen, Germany.

Ulrike Brückner (U)

Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital, Giessen, Germany.

Stephanie Schneider-Lauteren (S)

Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital, Giessen, Germany.

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Classifications MeSH