Identification and characterization of a novel nanobody against duck hepatitis A virus type 1.

Animals Cell Surface Display Techniques Ducks Epitopes, B-Lymphocyte / immunology Hepatitis Virus, Duck / immunology Hepatitis, Viral, Animal / diagnosis Poultry Diseases / virology Single-Domain Antibodies / isolation & purification Viral Structural Proteins / immunology
DHAV-1 Epitope Nanobody Phage display VP1

Journal

Virology
ISSN: 1096-0341
Titre abrégé: Virology
Pays: United States
ID NLM: 0110674

Informations de publication

Date de publication:
02 2019
Historique:
received: 29 08 2018
revised: 17 12 2018
accepted: 18 12 2018
pubmed: 28 12 2018
medline: 21 3 2019
entrez: 28 12 2018
Statut: ppublish

Résumé

Duck virus hepatitis (DVH) caused by duck hepatitis A virus type 1 (DHAV-1) is an acute and highly contagious disease affecting young ducklings. The VP1 protein is one of the major structural proteins of DHAV-1 carries critical epitopes responsible for the induction of neutralizing antibodies. In this study, we have successfully constructed an immune phage display VHHs library against DHAV-1 with the size of 6 × 10

Identifiants

DOI: 10.1016/j.virol.2018.12.013 PMID: 30590261
pubmed: 30590261
pii: S0042-6822(18)30376-3
doi: 10.1016/j.virol.2018.12.013
pii:
doi:

Substances chimiques

Epitopes, B-Lymphocyte 0
Single-Domain Antibodies 0
Viral Structural Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

101-109

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Wenxiang Xue (W)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Qin Zhao (Q)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, Yangling, Shanxi 712100, China.

Pengfei Li (P)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Ruihua Zhang (R)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Jingjing Lan (J)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Jingyu Wang (J)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Xiaoxue Yang (X)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Zhijing Xie (Z)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China.

Shijin Jiang (S)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Shandong, Taian 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong, Taian 271018, China. Electronic address: sjjiang@sdau.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Identification and characterization of a novel...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Ingénierie des protéines › Techniques d'exposition à la surface cellulaire › Identification and characterization of a novel...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Oiseaux › Canards › Identification and characterization of a novel...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Déterminants antigéniques des lymphocytes B › Identification and characterization of a novel...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Picornaviridae › Enterovirus › Virus de l'hépatite du canard › Identification and characterization of a novel...
questionsmedicales.fr › Maladies de l'animal › Hépatite animale › Hépatite virale animale › Identification and characterization of a novel...
questionsmedicales.fr › Maladies de l'animal › Maladies des oiseaux › Maladies de la volaille › Identification and characterization of a novel...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Fragments d'immunoglobuline › Fragments Fab d'immunoglobuline › Anticorps à domaine unique › Identification and characterization of a novel...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Identification and characterization of a novel...