Nanoparticles having amphiphilic silane containing Chlorin e6 with strong anti-biofilm activity against periodontitis-related pathogens.
Amphiphilic silane
Antibacterial
Magnetic targeting
Periodontitis
Photodynamic therapy
Photosensitizer
Journal
Journal of dentistry
ISSN: 1879-176X
Titre abrégé: J Dent
Pays: England
ID NLM: 0354422
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
03
10
2018
revised:
12
12
2018
accepted:
18
12
2018
pubmed:
30
12
2018
medline:
27
11
2019
entrez:
30
12
2018
Statut:
ppublish
Résumé
The objectives of this study were to: (1) develop the multifunctional nanoparticles containing Chlorin e6 (Ce6), Coumarin 6 (C6) and Fe Ce6 and C6 were co-loaded into the Fe Fe The multifunctional nanoparticles exerted strong anti-biofilm activity against periodontitis-related pathogens, with excellent biocompatibility, real-time monitoring, and magnetically-targeting capacities. The multifunctional nanoparticles have great potential in antibacterial applications to inhibit the occurrence and progression of periodontitis.
Identifiants
pubmed: 30593855
pii: S0300-5712(18)30542-6
doi: 10.1016/j.jdent.2018.12.011
pii:
doi:
Substances chimiques
Chlorophyllides
0
Porphyrins
0
Silanes
0
phytochlorin
5S2CCF3T1Z
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
70-84Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.