Neonatal Acute Liver Failure Associated with Angioinvasive Hepatic Zygomycosis.
fungal disease
neonatal acute liver failure
zygomycosis
Journal
Fetal and pediatric pathology
ISSN: 1551-3823
Titre abrégé: Fetal Pediatr Pathol
Pays: England
ID NLM: 101230972
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
pubmed:
1
1
2019
medline:
18
12
2019
entrez:
1
1
2019
Statut:
ppublish
Résumé
Neonatal acute liver failure (NALF) is often a fatal condition. Zygomycosis is a fungal infection that is often fatal in both adults and infants. Only a few cases of hepatic zygomycosis are reported in the literature and they are invariably associated with immunosuppression. Post-mortem liver biopsy from a 14-day old neonate demonstrated confluent panacinar necrosis with angioinvasive zygomycosis. The limited work-up could not rule out an underlying immunodeficiency. Angioinvasive hepatic zygomycosis can present in the neonatal period as NALF.
Sections du résumé
BACKGROUND
BACKGROUND
Neonatal acute liver failure (NALF) is often a fatal condition. Zygomycosis is a fungal infection that is often fatal in both adults and infants. Only a few cases of hepatic zygomycosis are reported in the literature and they are invariably associated with immunosuppression.
MATERIALS AND METHODS
METHODS
Post-mortem liver biopsy from a 14-day old neonate demonstrated confluent panacinar necrosis with angioinvasive zygomycosis. The limited work-up could not rule out an underlying immunodeficiency.
CONCLUSION
CONCLUSIONS
Angioinvasive hepatic zygomycosis can present in the neonatal period as NALF.
Identifiants
pubmed: 30595071
doi: 10.1080/15513815.2018.1556368
doi:
Substances chimiques
Antifungal Agents
0
Fungal Proteins
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM