A novel alignment procedure to assess calcified coronary plaques in histopathology, post-mortem computed tomography angiography and optical coherence tomography.
Autopsy
Biopsy
Computed Tomography Angiography
/ methods
Coronary Angiography
/ methods
Coronary Artery Disease
/ diagnostic imaging
Coronary Vessels
/ diagnostic imaging
Humans
Multimodal Imaging
Plaque, Atherosclerotic
Predictive Value of Tests
Radiographic Image Interpretation, Computer-Assisted
/ methods
Reproducibility of Results
Tomography, Optical Coherence
/ methods
Vascular Calcification
/ diagnostic imaging
Alignment
Calcified coronary plaques
Histopathology
Optical coherence tomography
Postmortem-computed tomography angiography
Journal
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
ISSN: 1879-1336
Titre abrégé: Cardiovasc Pathol
Pays: United States
ID NLM: 9212060
Informations de publication
Date de publication:
Historique:
received:
25
09
2018
revised:
30
10
2018
accepted:
30
11
2018
pubmed:
1
1
2019
medline:
7
5
2019
entrez:
1
1
2019
Statut:
ppublish
Résumé
Improve mapping and registration of longitudinal view on histopathology vessels in a three-dimensional alignment procedure for postmortem quantitative coronary plaque analyses. This new procedure is applied and results shown using calcified coronary plaque analyses within post-mortem computed tomography angiography (PMCTA), optical coherence tomography (OCT) and the gold standard of histopathology. In total, 338 annotated histopathology images were included, 166 PMCTA transversal images and 285 OCT images were aligned in the comparison. The results from the comparison using the alignment procedure showed overall that the calcified plaques seem to be overestimated by PMCTA and underestimated by OCT. The 3D fusion approach, aligning the images of PMCTA, OCT and histopathology as gold standard allowed for a slice-based comparison of the different modalities. The results showed that PMCTA overestimates the calcified plaques while OCT underestimates these, compared to histopathology.
Identifiants
pubmed: 30597423
pii: S1054-8807(18)30284-9
doi: 10.1016/j.carpath.2018.11.005
pii:
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
25-29Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.