Uncontrolled deceased cardiac donation: An unutilized source for organ transplantation in the United States.


Journal

Clinical transplantation
ISSN: 1399-0012
Titre abrégé: Clin Transplant
Pays: Denmark
ID NLM: 8710240

Informations de publication

Date de publication:
03 2019
Historique:
received: 30 10 2018
revised: 12 12 2018
accepted: 20 12 2018
pubmed: 1 1 2019
medline: 2 5 2020
entrez: 1 1 2019
Statut: ppublish

Résumé

The practice of uncontrolled donation after cardiac death (uDCD) has been met with tepid interest within the United States transplant community. Hesitancy stems largely from fears of eroding public trust due to complex ethical issues involving consent. Beyond ethical concerns, uDCD creates unique logistic challenges to obtain and to preserve organs within a short time frame. This mandates that organ recovery centers be able to rapidly mobilize, and that traditional cold preservation techniques may be inadequate. Proof of effective uDCD organ recovery comes from several European nations, and the frequency of its use is increasing due to early promising results. These scarce resources provide life-saving organs to desperate transplant candidates who otherwise experience high morbidity and mortality on a transplant waitlist. The objective of this review will be to provide an overview of the European experience with uDCD and discuss the unique ethical and logistic challenges associated with its implementation in the United States. Given existing models for it successful use, uDCD remains a poorly utilized source of donors in the United States at this time.

Identifiants

pubmed: 30597670
doi: 10.1111/ctr.13474
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13474

Informations de copyright

© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Auteurs

Rashikh A Choudhury (RA)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

Kas Prins (K)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

Hunter B Moore (HB)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

Dor Yoeli (D)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

Adi Kam (A)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

Trevor L Nydam (TL)

Division of Transplant Surgery, Department of Surgery, University of Colorado Hospital, Aurora, Colorado.

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Classifications MeSH