Unintentional Pediatric Marijuana Exposures at a Tertiary Care Children's Hospital in Washington State: A Retrospective Review.


Journal

Pediatric emergency care
ISSN: 1535-1815
Titre abrégé: Pediatr Emerg Care
Pays: United States
ID NLM: 8507560

Informations de publication

Date de publication:
01 Oct 2021
Historique:
pubmed: 3 1 2019
medline: 5 10 2021
entrez: 3 1 2019
Statut: ppublish

Résumé

Recreational marijuana became commercially available in Washington State in 2014. Children with marijuana intoxication can have lethargy and altered mental status, often resulting in extensive workup. The aim of this study was to quantify the incidence of pediatric marijuana exposure before and after marijuana legalization/commercial availability in Washington State at a tertiary care children's hospital. Charts of patients 9 years or younger evaluated at a tertiary care pediatric hospital from October 8, 2007, to October 31, 2016, were retrospectively reviewed. Inclusion criteria were positive tetrahydrocannabinol urine toxicology screen and diagnosis consistent with unintentional marijuana exposure. Data included age, sex, exposure date range, symptoms, ancillary tests, consults, disposition, and marijuana source. Data were analyzed in R using descriptive statistics. Seventeen unintentional marijuana exposures were identified during our study period, 8 cases before and 9 cases after legalization of recreational marijuana, which is 1.19 events per year in the 6.75 years before legalization compared with 3.88 events per year in the 2.32 years after (P < 0.05). Age range was 17 months to 7 years, with a median age of 21 months. Eighty-two percent received laboratory tests, 47% underwent head computed tomography, 6% underwent lumbar puncture, and 100% underwent social work evaluation. Thirty-five percent were discharged from the emergency department, 47% were admitted to general medicine, and 18% were admitted to the critical care unit. Unintentional marijuana exposure incidence increased after legalization of recreational marijuana in Washington State at a tertiary care children's hospital. Providers should be aware of this increasing incidence. These data should be considered in the drafting of future marijuana legislation.

Sections du résumé

BACKGROUND BACKGROUND
Recreational marijuana became commercially available in Washington State in 2014. Children with marijuana intoxication can have lethargy and altered mental status, often resulting in extensive workup.
OBJECTIVES OBJECTIVE
The aim of this study was to quantify the incidence of pediatric marijuana exposure before and after marijuana legalization/commercial availability in Washington State at a tertiary care children's hospital.
METHODS METHODS
Charts of patients 9 years or younger evaluated at a tertiary care pediatric hospital from October 8, 2007, to October 31, 2016, were retrospectively reviewed. Inclusion criteria were positive tetrahydrocannabinol urine toxicology screen and diagnosis consistent with unintentional marijuana exposure. Data included age, sex, exposure date range, symptoms, ancillary tests, consults, disposition, and marijuana source. Data were analyzed in R using descriptive statistics.
RESULTS RESULTS
Seventeen unintentional marijuana exposures were identified during our study period, 8 cases before and 9 cases after legalization of recreational marijuana, which is 1.19 events per year in the 6.75 years before legalization compared with 3.88 events per year in the 2.32 years after (P < 0.05). Age range was 17 months to 7 years, with a median age of 21 months. Eighty-two percent received laboratory tests, 47% underwent head computed tomography, 6% underwent lumbar puncture, and 100% underwent social work evaluation. Thirty-five percent were discharged from the emergency department, 47% were admitted to general medicine, and 18% were admitted to the critical care unit.
CONCLUSIONS CONCLUSIONS
Unintentional marijuana exposure incidence increased after legalization of recreational marijuana in Washington State at a tertiary care children's hospital. Providers should be aware of this increasing incidence. These data should be considered in the drafting of future marijuana legislation.

Identifiants

pubmed: 30601351
pii: 00006565-202110000-00013
doi: 10.1097/PEC.0000000000001703
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e594-e598

Informations de copyright

Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure: The authors declare no conflict of interest.

Références

Substance Abuse and Mental Health Services Administration (SAMHSA). Marijuana (Cannabis). November 2016. Available at: http://www.samhsa.gov/atod/marijuana . Accessed April 16, 2017.
Ashton CH. Pharmacology and effects of cannabis: a brief review. Br J Psychiatry . 2001;178:101–106.
Borgelt LM, Franson KL, Nussbaum AM, et al. The pharmacologic and clinical effects of medical cannabis. Pharmacotherapy . 2013;33:195–209.
Washington State Liquor and Cannabis Board. FAQs on marijuana. 2015. Available at: https://www.lcb.wa.gov/mj2015/faqs_i-502 . Accessed February 18, 2018.
Wang GS, Roosevelt G, Le Lait MC, et al. Association of unintentional pediatric exposures with decriminalization of marijuana in the United States. Ann Emerg Med . 2014;63:684–689.
Web-based Injury Statistics Query and Reporting System (WISQARS). Centers for Disease Control and Prevention. October 27, 2016. Available at: https://webappa.cdc.gov/cgi-bin/broker.exe . Accessed April 16, 2017.
Wang GS, Roosevelt G, Heard K. Pediatric marijuana exposures in a medical marijuana state. JAMA Pediatr . 2013;167:630–633.
Wang GS, Le Lait MC, Deaknye SJ, et al. Unintentional pediatric exposures to marijuana in Colorado, 2009–2015. JAMA Pediatr . 2016;170:e160971.
Onders B, Casavant MJ, Spiller HA, et al. Marijuana exposure among children younger than 6 years in the United States. Clin Pediatr (Phila) . 2016;55:428–436.
Blaudet I, Mouvier S, Labadie M, et al. Unintentional cannabis intoxication in toddlers. Pediatrics . 2017;140:e20170017.
Washington Poison Center. 2015 Annual cannabis report. April 1, 2017. Available at: http://www.wapc.org/toxic-trends/marijuana-and-you/2015annualcannabisreport/ . Accessed April 16, 2017.
Fay MP. Two-sided exact tests and matching confidence intervals for discrete data. R Journal . 2010;2:53–58.
Washington Poison Center. Toxic trends report: 2016 annual cannabis report. February 14, 2017. Available at: https://www.wapc.org/wp-content/uploads/Cannabis-Report.pdf . Accessed September 18, 2017.

Auteurs

Anita Anne Thomas (AA)

From the Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Washington/Seattle Children's Hospital, Seattle, WA.

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