Clinical evaluation of two dark blood methods of late gadolinium quantification of ischemic scar.
bright blood
dark blood
ischemic heart disease
late gadolinium enhancement
myocardial infarction
Journal
Journal of magnetic resonance imaging : JMRI
ISSN: 1522-2586
Titre abrégé: J Magn Reson Imaging
Pays: United States
ID NLM: 9105850
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
13
09
2018
revised:
25
11
2018
accepted:
26
11
2018
pubmed:
4
1
2019
medline:
15
8
2020
entrez:
4
1
2019
Statut:
ppublish
Résumé
Late gadolinium enhancement (LGE) imaging was validated for diagnosis and quantification of myocardial infarction (MI). Despite good contrast between scar and normal myocardium, contrast between blood pool and myocardial scar can be limited. Dark blood LGE sequences attempt to overcome this issue. To evaluate T Prospective. Thirty patients with prior MI. Patients underwent identical 1.5 T MRI protocols. Following routine LGE imaging, a slice with scar, remote myocardium, and blood pool was selected. PSIR LGE was repeated with inversion time set to MN, to BN, and T Three observers. Qualitative assessment of confidence scores in scar detection and degree of transmurality. Quantitative assessment of myocardial scar mass (grams), and contrast-to-noise ratio (CNR) measurements between scar, blood pool, and myocardium. Repeated-measures analysis of variance (ANOVA) with Bonferroni correction, coefficient of variation, and the Cohen κ statistic. CNR PSIR with inversion time (TI) set for blood nulling and the T 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:146-152.
Sections du résumé
BACKGROUND
Late gadolinium enhancement (LGE) imaging was validated for diagnosis and quantification of myocardial infarction (MI). Despite good contrast between scar and normal myocardium, contrast between blood pool and myocardial scar can be limited. Dark blood LGE sequences attempt to overcome this issue.
PURPOSE
To evaluate T
STUDY TYPE
Prospective.
POPULATION
Thirty patients with prior MI.
FIELD STRENGTH/SEQUENCE
Patients underwent identical 1.5 T MRI protocols. Following routine LGE imaging, a slice with scar, remote myocardium, and blood pool was selected. PSIR LGE was repeated with inversion time set to MN, to BN, and T
ASSESSMENT
Three observers. Qualitative assessment of confidence scores in scar detection and degree of transmurality. Quantitative assessment of myocardial scar mass (grams), and contrast-to-noise ratio (CNR) measurements between scar, blood pool, and myocardium.
STATISTICAL TESTS
Repeated-measures analysis of variance (ANOVA) with Bonferroni correction, coefficient of variation, and the Cohen κ statistic.
RESULTS
CNR
DATA CONCLUSION
PSIR with inversion time (TI) set for blood nulling and the T
LEVEL OF EVIDENCE
2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:146-152.
Substances chimiques
Contrast Media
0
Organometallic Compounds
0
gadobutrol
1BJ477IO2L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
146-152Subventions
Organisme : British Heart Foundation
ID : RG/16/1/32092
Pays : United Kingdom
Informations de copyright
© 2019 International Society for Magnetic Resonance in Medicine.