Extended cardiac ambulatory rhythm monitoring in adults with congenital heart disease: Arrhythmia detection and impact of extended monitoring.


Journal

Congenital heart disease
ISSN: 1747-0803
Titre abrégé: Congenit Heart Dis
Pays: United States
ID NLM: 101256510

Informations de publication

Date de publication:
May 2019
Historique:
received: 21 06 2018
revised: 07 10 2018
accepted: 29 11 2018
pubmed: 4 1 2019
medline: 3 1 2020
entrez: 4 1 2019
Statut: ppublish

Résumé

Arrhythmias are a leading cause of death in adults with congenital heart disease (ACHD). While 24-48-hour monitors are often used to assess arrhythmia burden, extended continuous ambulatory rhythm monitors (ECAM) can record 2 weeks of data. The utility of this device and the arrhythmia burden identified beyond 48-hour monitoring have not been evaluated in the ACHD population. Additionally, the impact of ECAM has not been studied to determine management recommendations. To address the preliminary question, we hypothesized that clinically significant arrhythmias would be detected on ECAM beyond 48 hours and this would lead to clinical management changes. A single center retrospective cohort study of ACHD patients undergoing ECAM from June 2013 to May 2016 was performed. The number and type of arrhythmias detected within and beyond the first 48 hours of monitoring were compared using Kaplan-Meier curves and Cox proportional hazard models. Three hundred fourteen patients had monitors performed [median age 31 (IQR 25-41) years, 61% female). Significant arrhythmias were identified in 156 patients (50%), of which 46% were noted within 48 hours. A management change based on an arrhythmia was made in 49 patients (16%). ECAM detects more clinically significant arrhythmias than standard 48-hour monitoring in ACHD patients. Management changes, including medication changes, further testing or imaging, and procedures, were made based on results of ECAM. Recommendations and guidelines have been made based on arrhythmias on 48-hour monitoring; the predictive ability and clinical consequence of arrhythmias found on ECAM are not yet known.

Sections du résumé

BACKGROUND BACKGROUND
Arrhythmias are a leading cause of death in adults with congenital heart disease (ACHD). While 24-48-hour monitors are often used to assess arrhythmia burden, extended continuous ambulatory rhythm monitors (ECAM) can record 2 weeks of data. The utility of this device and the arrhythmia burden identified beyond 48-hour monitoring have not been evaluated in the ACHD population. Additionally, the impact of ECAM has not been studied to determine management recommendations.
OBJECTIVE OBJECTIVE
To address the preliminary question, we hypothesized that clinically significant arrhythmias would be detected on ECAM beyond 48 hours and this would lead to clinical management changes.
METHODS METHODS
A single center retrospective cohort study of ACHD patients undergoing ECAM from June 2013 to May 2016 was performed. The number and type of arrhythmias detected within and beyond the first 48 hours of monitoring were compared using Kaplan-Meier curves and Cox proportional hazard models.
RESULTS RESULTS
Three hundred fourteen patients had monitors performed [median age 31 (IQR 25-41) years, 61% female). Significant arrhythmias were identified in 156 patients (50%), of which 46% were noted within 48 hours. A management change based on an arrhythmia was made in 49 patients (16%).
CONCLUSIONS CONCLUSIONS
ECAM detects more clinically significant arrhythmias than standard 48-hour monitoring in ACHD patients. Management changes, including medication changes, further testing or imaging, and procedures, were made based on results of ECAM. Recommendations and guidelines have been made based on arrhythmias on 48-hour monitoring; the predictive ability and clinical consequence of arrhythmias found on ECAM are not yet known.

Identifiants

pubmed: 30604934
doi: 10.1111/chd.12736
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

410-418

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Karen E Schultz (KE)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.

George K Lui (GK)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.

Doff B McElhinney (DB)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.

Jin Long (J)

Department of Medicine, Quantitative Sciences Unit, Stanford Univeristy, Stanford, California.

Vidhya Balasubramanian (V)

Department of Medicine, Quantitative Sciences Unit, Stanford Univeristy, Stanford, California.

Charlotte Sakarovitch (C)

Department of Medicine, Quantitative Sciences Unit, Stanford Univeristy, Stanford, California.

Susan M Fernandes (SM)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.

Anne M Dubin (AM)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.

Ian S Rogers (IS)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.

Anitra W Romfh (AW)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.

Kara S Motonaga (KS)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.

Mohan N Viswanathan (MN)

Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.

Scott R Ceresnak (SR)

Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Lucile Packard Children's Hospital, Stanford, California.

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