The NeuroDev Study: Phenotypic and Genetic Characterization of Neurodevelopmental Disorders in Kenya and South Africa.


Journal

Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320

Informations de publication

Date de publication:
02 01 2019
Historique:
entrez: 4 1 2019
pubmed: 4 1 2019
medline: 21 8 2019
Statut: ppublish

Résumé

The NeuroDev study will deeply phenotype cognition, behavior, dysmorphias, and neuromedical traits on an expected cohort of 5,600 Africans (1,800 child cases, 1,800 child controls, and 1,900 parents) and will collect whole blood for exome sequencing and biobanking.

Identifiants

pubmed: 30605655
pii: S0896-6273(18)31116-4
doi: 10.1016/j.neuron.2018.12.016
pmc: PMC7191973
mid: NIHMS1560792
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Pagination

15-19

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 205419/Z/16/Z
Pays : United Kingdom
Organisme : NIAAA NIH HHS
ID : R01 AA026834
Pays : United States
Organisme : NIMH NIH HHS
ID : U01 MH119689
Pays : United States

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Références

Afr J Psychiatry (Johannesbg). 2011 Jul;14(3):208-10
pubmed: 21863205
Lancet Psychiatry. 2016 Sep;3(9):800-2
pubmed: 27568261
BMC Med Ethics. 2015 Jul 02;16:45
pubmed: 26135122
Lancet Neurol. 2014 Oct;13(10):1029-44
pubmed: 25231525
EBioMedicine. 2015 Oct 09;2(10):1259-61
pubmed: 26629498
Alcohol Clin Exp Res. 2013 May;37(5):818-30
pubmed: 23241076
Nat Genet. 2017 Apr;49(4):504-510
pubmed: 28191890
Nature. 2018 Oct;562(7726):268-271
pubmed: 30258228
Genet Med. 2016 Nov;18(11):1085-1087
pubmed: 26938780

Auteurs

Victoria de Menil (V)

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA.

Michelle Hoogenhout (M)

Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa.

Patricia Kipkemoi (P)

Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.

Dorcas Kamuya (D)

Department of Health Systems and Research Ethics, KEMRI-Wellcome Trust Collaborative Research Programme, Kilifi, Kenya.

Emma Eastman (E)

Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa.

Alice Galvin (A)

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

Katini Mwangasha (K)

Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.

Jantina de Vries (J)

Department of Medicine, University of Cape Town, Observatory, Cape Town 7925, South Africa.

Symon M Kariuki (SM)

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK; Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.

Serini Murugasen (S)

Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa.

Paul Mwangi (P)

Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.

Ilina Singh (I)

Department of Psychiatry and Wellcome Centre for Ethics and Humanities, University of Oxford, Oxford, UK.

Dan J Stein (DJ)

Department of Psychiatry & Mental Health, and MRC Unit on Risk and Resilience in Mental Disorders, University of Cape Town, J-Block, Groote Schuur Hospital, Observatory, Cape Town, South Africa.

Amina Abubakar (A)

Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya. Electronic address: aabubakar@kemri-wellcome.org.

Charles R Newton (CR)

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK; Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.

Kirsten A Donald (KA)

Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa. Electronic address: kirsty.donald@uct.ac.za.

Elise Robinson (E)

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Richard B. Simches Building, 6(th) Floor, 185 Cambridge Street, Boston, MA 02114, USA. Electronic address: erob@broadinstitute.org.

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