Resveratrol potentially increased the tumoricidal effect of doxorubicin on SKOV3 cancer stem cells in vitro.

cancer stem cells doxorubicin drug resistance resveratrol

Journal

Journal of cellular biochemistry
ISSN: 1097-4644
Titre abrégé: J Cell Biochem
Pays: United States
ID NLM: 8205768

Informations de publication

Date de publication:
May 2019
Historique:
received: 24 08 2018
accepted: 31 10 2018
pubmed: 5 1 2019
medline: 5 1 2019
entrez: 5 1 2019
Statut: ppublish

Résumé

Ovarian cancer is associated with a high percentage of recurrence of tumor and resistance to chemotherapy. Cancer stem cells (CSCs) form a rare population with a significant capacity to begin and expand malignant diseases. Eliminating the drug resistance of CSCs by factors that have fewer side effects to the patient is vital. To investigate the effect of resveratrol (RES) and doxorubicin (DOX) on drug resistance and apoptosis of CSCs; at the first, isolation of CSCs from SKOV3 ovarian carcinoma cells and their dosage adjustment (IC

Identifiants

pubmed: 30609135
doi: 10.1002/jcb.28129
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8430-8437

Subventions

Organisme : Tabriz University of Medical Sciences
ID : 95/86

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Ayda Pouyafar (A)

Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Milad Zadi Heydarabad (M)

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Sina Bahar Aghdam (SB)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Majid Khaksar (M)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Ako Azimi (A)

Department of Basic Sciences, Maragheh University of Medical Sciences, Maragheh, Iran.

Reza Rahbarghazi (R)

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Mehdi Talebi (M)

Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Immunology, Tabriz University of Medical Sciences, Tabriz, Iran.

Classifications MeSH