Evaluation of different competitive immunoassays for aflatoxin M
Aflatoxin M(1)
Competitive immunoassay
Hapten
Inductively coupled plasma mass spectrometry
Nanoparticle
Journal
Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534
Informations de publication
Date de publication:
21 Feb 2019
21 Feb 2019
Historique:
received:
10
04
2018
revised:
09
11
2018
accepted:
12
11
2018
entrez:
8
1
2019
pubmed:
8
1
2019
medline:
6
3
2019
Statut:
ppublish
Résumé
Haptens (i.e. biomolecules which molecular weight is lower than 10 kDa) determination by inductively coupled plasma mass spectrometry (ICP-MS) is usually performed by means of competitive immunoassays. In these immunoassays, analyte quantification is indirectly carried out using two different tracer species (i.e. antibodies or antigen-protein conjugates). However, the benefits (and drawbacks) derived from using a given tracer species have not been systematically investigated so far. The goal of this work is to evaluate the influence of the tracer species employed in competitive immunoassays on the analytical figures of merit for aflatoxin M
Identifiants
pubmed: 30612640
pii: S0003-2670(18)31363-1
doi: 10.1016/j.aca.2018.11.024
pii:
doi:
Substances chimiques
Antibodies
0
Silver
3M4G523W1G
Aflatoxin M1
6795-23-9
Gold
7440-57-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
10-19Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.