Phrenic Nerve Conduction in Healthy Subjects.


Journal

Muscle & nerve
ISSN: 1097-4598
Titre abrégé: Muscle Nerve
Pays: United States
ID NLM: 7803146

Informations de publication

Date de publication:
04 2019
Historique:
received: 21 03 2018
revised: 26 12 2018
accepted: 05 01 2019
pubmed: 10 1 2019
medline: 6 7 2019
entrez: 10 1 2019
Statut: ppublish

Résumé

Assessment of diaphragm compound muscle action potential by noninvasive phrenic nerve stimulation at the neck is well described. However, normal values in a large cohort of healthy subjects are lacking. Our objective was to determine reference values of phrenic nerve conduction in healthy subjects. We recruited 155 healthy subjects (25-79 years old) and measured mean amplitude (PhrenAmp) and latency (PhrenLat) of motor responses according to Bolton's method. The lower limit for PhrenAmp was 0.28 and 0.25 mV and the upper limit for PhrenLat was 8.41 and 8.56 ms for right and left side, respectively. PhrenLat was correlated with age. PhrenAmp, PhrenLat and area were significantly higher in men. Tolerance to phrenic nerve stimulation was excellent. Our study provides normative values of phrenic nerve motor responses in a large cohort of healthy subjects and identifies age and sex as factors of variation. Muscle Nerve 59:451-456, 2019.

Identifiants

pubmed: 30623462
doi: 10.1002/mus.26414
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

451-456

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Marjolaine Vincent (M)

Service de Pneumologie et Oncologie Thoracique, CHU St-Etienne, France.

Isabelle Court-Fortune (I)

Service de Pneumologie et Oncologie Thoracique, CHU St-Etienne, France.

Frédéric Costes (F)

UCA, INRA UMR 1019, Equipe ASMS, Clermont Ferrand, France.

Jean-Christophe Antoine (JC)

Service de Neurologie, CHU St-Etienne, France.

Jean-Philippe Camdessanché (JP)

Service de Neurologie, CHU St-Etienne, France.

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Classifications MeSH