Cooperative predation in the social amoebae Dictyostelium discoideum.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2019
2019
Historique:
received:
24
08
2018
accepted:
05
12
2018
entrez:
10
1
2019
pubmed:
10
1
2019
medline:
24
9
2019
Statut:
epublish
Résumé
The eukaryotic amoeba Dictyostelium discoideum is commonly used to study sociality. The amoebae cooperate during development, exhibiting altruism, cheating, and kin-discrimination, but growth while preying on bacteria has been considered asocial. Here we show that Dictyostelium are cooperative predators. Using mutants that grow poorly on Gram-negative bacteria but grow well on Gram-positive bacteria, we show that growth depends on cell-density and on prey type. We also found synergy, by showing that pairwise mixes of different mutants grow well on live Gram-negative bacteria. Moreover, wild-type amoebae produce diffusible factors that facilitate mutant growth and some mutants exploit the wild type in mixed cultures. Finding cooperative predation in D. discoideum should facilitate studies of this fascinating phenomenon, which has not been amenable to genetic analysis before.
Identifiants
pubmed: 30625171
doi: 10.1371/journal.pone.0209438
pii: PONE-D-18-24960
pmc: PMC6326426
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0209438Subventions
Organisme : NIGMS NIH HHS
ID : K12 GM084897
Pays : United States
Organisme : NICHD NIH HHS
ID : P01 HD039691
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM118016
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008231
Pays : United States
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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