The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice.
BALB/C mice
behavioural testing
learning
memory
nanotoxicity
silver nanoparticles
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
08 01 2019
08 01 2019
Historique:
received:
20
11
2018
revised:
23
12
2018
accepted:
04
01
2019
entrez:
11
1
2019
pubmed:
11
1
2019
medline:
9
5
2019
Statut:
epublish
Résumé
Silver Nanoparticles (AgNPs), an epitome of nanotechnology, appear in everyday products such as water filters, printer ink, toothpaste, food packaging and cosmetics mostly due to their bactericidal properties. Given this high level of public exposure, the safety of AgNPs has never been fully established. The unsafe use of AgNPs could pose a real threat, not only to public health but also to economic growth in many industries. In this paper, we tested the effect of AgNPs on memory, learning, social behaviour and motor function of BALB/C mice. Outcomes of the present study suggested an impairment of these functions in AgNPs treated groups. Overall, obtained data support the evidence that the systemic exposure to AgNPs may result in alteration of the cerebral cognition and warrants further consideration on the impact of the AgNPs on human health with respect to their potential neurotoxicity.
Identifiants
pubmed: 30625980
pii: ijerph16010148
doi: 10.3390/ijerph16010148
pmc: PMC6339045
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Environmental Pollutants
0
Silver
3M4G523W1G
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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