Standard work-up of the low-risk kidney transplant candidate: a European expert survey of the ERA-EDTA Developing Education Science and Care for Renal Transplantation in European States Working Group.


Journal

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ISSN: 1460-2385
Titre abrégé: Nephrol Dial Transplant
Pays: England
ID NLM: 8706402

Informations de publication

Date de publication:
01 09 2019
Historique:
received: 19 08 2018
pubmed: 11 1 2019
medline: 26 3 2020
entrez: 11 1 2019
Statut: ppublish

Résumé

Existing guidelines on the evaluation and preparation of recipients for kidney transplantation target the entire spectrum of patients with end-stage renal disease. Within the ERA-EDTA Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) Working Group, it was proposed that in a subset of relatively young patients (<40 years) without significant comorbidities (such as diabetes or cardiovascular disease), the work-up for transplantation could be restricted to a small set of tests. Aiming for agreement between transplant centres across Europe, we surveyed the opinion of 80 transplant professionals from 11 European states on the composition of a minimal work-up. We show that there is a wide agreement among European experts that the work-up for kidney transplantation of the low-risk candidate, as opposed to the standard risk candidate, could include a limited number of investigations. However, there is some disagreement regarding the small number of diagnostic procedures, which is related to geographical location within Europe and the professional background of respondents. Based on the results of the survey, published guidelines and expert meetings by the DESCARTES Working Group, we have formulated a proposal for the work-up of low-risk kidney transplant candidates.

Sections du résumé

BACKGROUND
Existing guidelines on the evaluation and preparation of recipients for kidney transplantation target the entire spectrum of patients with end-stage renal disease. Within the ERA-EDTA Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) Working Group, it was proposed that in a subset of relatively young patients (<40 years) without significant comorbidities (such as diabetes or cardiovascular disease), the work-up for transplantation could be restricted to a small set of tests.
METHODS
Aiming for agreement between transplant centres across Europe, we surveyed the opinion of 80 transplant professionals from 11 European states on the composition of a minimal work-up.
RESULTS
We show that there is a wide agreement among European experts that the work-up for kidney transplantation of the low-risk candidate, as opposed to the standard risk candidate, could include a limited number of investigations. However, there is some disagreement regarding the small number of diagnostic procedures, which is related to geographical location within Europe and the professional background of respondents.
CONCLUSIONS
Based on the results of the survey, published guidelines and expert meetings by the DESCARTES Working Group, we have formulated a proposal for the work-up of low-risk kidney transplant candidates.

Identifiants

pubmed: 30629182
pii: 5281215
doi: 10.1093/ndt/gfy391
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1605-1611

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Auteurs

Umberto Maggiore (U)

Department of Nephrology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.

Daniel Abramowicz (D)

Department of Nephrology, Antwerp University Hospital, Antwerp University, Antwerp, Belgium.

Klemens Budde (K)

Department of Nephrology, Charité Medical University Berlin, Berlin, Germany.

Marta Crespo (M)

Department of Nephrology, Hospital del Mar Barcelona, Barcelona, Spain.

Christophe Mariat (C)

Department of Nephrology, Dialysis, and Renal Transplantation, University North Hospital, Saint Etienne, France.

Rainer Oberbauer (R)

Department of Nephrology, Medical University of Vienna, Vienna, Austria.

Julio Pascual (J)

Department of Nephrology, Hospital del Mar Barcelona, Barcelona, Spain.

Licia Peruzzi (L)

Pediatric Nephrology Unit, Regina Margherita Children's Hospital, Turin, Italy.

Soren Schwartz Sorensen (S)

Department of Nephrology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Ondrej Viklicky (O)

Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

Bruno Watschinger (B)

Department of Nephrology, Medical University of Vienna, Vienna, Austria.

Gabriel C Oniscu (GC)

Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.

Uwe Heemann (U)

Department of Nephrology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Luuk B Hilbrands (LB)

Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.

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