Factors Associated With Opioid Use in Presurgical Knee, Hip, and Spine Osteoarthritis Patients.


Journal

Arthritis care & research
ISSN: 2151-4658
Titre abrégé: Arthritis Care Res (Hoboken)
Pays: United States
ID NLM: 101518086

Informations de publication

Date de publication:
09 2019
Historique:
received: 18 07 2018
accepted: 08 01 2019
pubmed: 11 1 2019
medline: 18 3 2020
entrez: 11 1 2019
Statut: ppublish

Résumé

To evaluate rates of prescription opioid use among patients with presurgical knee, hip, and spine osteoarthritis (OA) and associations between use and sociodemographic and health status characteristics. Participants were patients with presurgical, end-stage OA of the knee (n = 77), hip (n = 459), and spine (n = 168). Data were collected on current use of opioids and other pain medications, as well as measures of sociodemographic and health status variables and depression and pain (0-10 numeric rating scale). Rates of opioid use were calculated by sex, age, and surgical site. Multivariable logistic regression was used to examine associations between opioid use (sometimes/daily versus never) and other study variables. The mean age of participants was 65.6 years; 55.5% were women, 15% of patients reported "sometimes" using opioids, and 15% reported "daily use." Use of opioids was highest among patients with spine OA (40%) and similar among patients with knee and hip OA (28% and 30%, respectively). Younger women (ages <65 years) reported the greatest use of opioids overall, particularly among patients with spine OA. From multivariable logistic regression, greater likelihood of opioid use was significantly associated with spine OA (versus knee OA), obesity, being a current or former smoker, higher symptomatic joint count, greater depressive symptoms, greater pain, and current use of other prescription pain medication. Nearly one-third of patients with presurgical OA used prescription opioid medication. Given the questionable efficacy of opioids in OA and risk of adverse effects, higher opioid use among younger individuals and those with depressive symptoms is of concern and warrants further investigation.

Identifiants

pubmed: 30629338
doi: 10.1002/acr.23831
doi:

Substances chimiques

Analgesics, Opioid 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1178-1185

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2019, American College of Rheumatology.

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Auteurs

J Denise Power (JD)

Arthritis Program and Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.

Anthony V Perruccio (AV)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Rajiv Gandhi (R)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Christian Veillette (C)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

J Roderick Davey (JR)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Stephen J Lewis (SJ)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Khalid Syed (K)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Nizar N Mahomed (NN)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Y Raja Rampersaud (YR)

Arthritis Program and Krembil Research Institute, University Health Network and University of Toronto, Toronto, Ontario, Canada.

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