Key Viral Adaptations Preceding the AIDS Pandemic.

Acquired Immunodeficiency Syndrome / immunology Adaptation, Physiological / genetics Animals Animals, Wild / virology Gorilla gorilla / virology HIV-1 / genetics HIV-2 / genetics Haplorhini / virology Host Specificity Humans Immunity, Innate Pan troglodytes / virology Pandemics / veterinary Primate Diseases / virology Recombination, Genetic Simian Acquired Immunodeficiency Syndrome / immunology Simian Immunodeficiency Virus / genetics Species Specificity Virus Replication Zoonoses / immunology
AIDS HIV adaptation arms race evolution primate lentiviruses restriction factors viral zoonoses

Journal

Cell host & microbe
ISSN: 1934-6069
Titre abrégé: Cell Host Microbe
Pays: United States
ID NLM: 101302316

Informations de publication

Date de publication:
09 01 2019
Historique:
entrez: 11 1 2019
pubmed: 11 1 2019
medline: 15 3 2019
Statut: ppublish

Résumé

HIV, the causative agent of AIDS, has a complex evolutionary history involving several cross-species transmissions and recombination events as well as changes in the repertoire and function of its accessory genes. Understanding these events and the adaptations to new host species provides key insights into innate defense mechanisms, viral dependencies on cellular factors, and prerequisites for the emergence of the AIDS pandemic. In addition, understanding the factors and adaptations required for the spread of HIV in the human population helps to better assess the risk of future lentiviral zoonoses and provides clues to how improved control of viral replication can be achieved. Here, we summarize our current knowledge on viral features and adaptations preceding the AIDS pandemic. We aim at providing a viral point of view, focusing on known key hurdles of each cross-species transmission and the mechanisms that HIV and its simian precursors evolved to overcome them.

Identifiants

DOI: 10.1016/j.chom.2018.12.002 PMID: 30629915
pubmed: 30629915
pii: S1931-3128(18)30629-2
doi: 10.1016/j.chom.2018.12.002
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

27-38

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Daniel Sauter (D)

Institute of Molecular Virology, Ulm University Medical Centre, Ulm 89081, Germany.

Frank Kirchhoff (F)

Institute of Molecular Virology, Ulm University Medical Centre, Ulm 89081, Germany. Electronic address: frank.kirchhoff@uni-ulm.de.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Syndrome d'immunodéficience acquise › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Groupes animaux › Animaux sauvages › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Gorilla gorilla › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-1 (Virus de l'Immunodéficience Humaine de type 1) › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-2 (Virus de l'Immunodéficience Humaine de type 2) › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes biologiques › Interactions hôte-microbes › Interactions hôte-pathogène › Spécificité d'hôte › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité innée › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Pan troglodytes › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Épidémies de maladies › Épidémies › Pandémies › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Maladies de l'animal › Maladies des primates › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes génétiques › Recombinaison génétique › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Maladies de l'animal › Maladies des primates › Maladies des singes › Syndrome d'immunodéficience acquise du singe › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Rétrovirus simiens › Virus de l'immunodéficience simienne › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes biologiques › Spécificité d'espèce › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › Key Viral Adaptations Preceding the AIDS Pandemic.
questionsmedicales.fr › Maladies de l'animal › Zoonoses › Key Viral Adaptations Preceding the AIDS Pandemic.