Emotion processing in Parkinson's disease: a blood oxygenation level-dependent functional magnetic resonance imaging study.
Blood oxygenation level-dependent functional magnetic resonance imaging
Parkinson's disease
activation
brain
dopamine
emotion
neural regeneration
processing
Journal
Neural regeneration research
ISSN: 1673-5374
Titre abrégé: Neural Regen Res
Pays: India
ID NLM: 101316351
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
entrez:
12
1
2019
pubmed:
12
1
2019
medline:
12
1
2019
Statut:
ppublish
Résumé
Parkinson's disease is a neurodegenerative disorder caused by loss of dopamine neurons in the substantia nigra pars compacta. Tremor, rigidity, and bradykinesia are the major symptoms of the disease. These motor impairments are often accompanied by affective and emotional dysfunctions which have been largely studied over the last decade. The aim of this study was to investigate emotional processing organization in the brain of patients with Parkinson's disease and to explore whether there are differences between recognition of different types of emotions in Parkinson's disease. We examined 18 patients with Parkinson's disease (8 men, 10 women) with no history of neurological or psychiatric comorbidities. All these patients underwent identical brain blood oxygenation level-dependent functional magnetic resonance imaging for emotion evaluation. Blood oxygenation level-dependent functional magnetic resonance imaging results revealed that the occipito-temporal cortices, insula, orbitofrontal cortex, basal ganglia, and parietal cortex which are involved in emotion processing, were activated during the functional control. Additionally, positive emotions activate larger volumes of the same anatomical entities than neutral and negative emotions. Results also revealed that Parkinson's disease associated with emotional disorders are increasingly recognized as disabling as classic motor symptoms. These findings help clinical physicians to recognize the emotional dysfunction of patients with Parkinson's disease.
Identifiants
pubmed: 30632507
pii: NeuralRegenRes_2019_14_4_666_247470
doi: 10.4103/1673-5374.247470
pmc: PMC6352597
doi:
Types de publication
Journal Article
Langues
eng
Pagination
666-672Déclaration de conflit d'intérêts
None
Références
Brain. 1999 May;122 ( Pt 5):883-93
pubmed: 10355673
Brain. 1999 Sep;122 ( Pt 9):1637-50
pubmed: 10468504
Neurology. 2000 Apr 11;54(7):1482-7
pubmed: 10751262
Brain. 2001 Jun;124(Pt 6):1125-30
pubmed: 11353728
Behav Neurol. 1998;11(1):29-42
pubmed: 11568400
Brain. 2002 Mar;125(Pt 3):584-94
pubmed: 11872615
Neuroimage. 2002 Jun;16(2):331-48
pubmed: 12030820
Neuropsychologia. 2003;41(8):1047-57
pubmed: 12667540
Semin Pediatr Neurol. 2003 Mar;10(1):3-10
pubmed: 12785742
Brain. 2003 Jul;126(Pt 7):1691-712
pubmed: 12805109
Mov Disord. 2003 Oct;18(10):1115-22
pubmed: 14534914
Int J Psychophysiol. 1992 Dec;13(3):225-32
pubmed: 1459879
Brain Res Cogn Brain Res. 2005 May;23(2-3):327-40
pubmed: 15820640
Biol Psychiatry. 2005 Jun 1;57(11):1377-84
pubmed: 15950011
Int J Psychophysiol. 2006 Apr;60(1):34-43
pubmed: 15993964
Clin Neurophysiol. 2006 Jan;117(1):94-102
pubmed: 16330254
Brain. 2006 Mar;129(Pt 3):707-17
pubmed: 16415306
Neuroimage. 2006 Jul 15;31(4):1625-36
pubmed: 16624584
Exp Brain Res. 2006 Aug;173(2):318-21
pubmed: 16710683
Hum Brain Mapp. 2007 Jan;28(1):69-84
pubmed: 16761271
Neuropsychologia. 2007 Jan 7;45(1):65-74
pubmed: 16780901
Trends Neurosci. 1990 Jul;13(7):266-71
pubmed: 1695401
Brain. 2006 Dec;129(Pt 12):3356-65
pubmed: 17095520
Brain Res. 2008 Jan 10;1188:100-11
pubmed: 18022608
J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):368-76
pubmed: 18344392
Neuropsychologia. 2008;46(9):2300-9
pubmed: 18485422
Neuroimage. 2008 Aug 15;42(2):998-1031
pubmed: 18579414
Eur Neuropsychopharmacol. 2008 Nov;18(11):835-48
pubmed: 18707851
J Cogn Neurosci. 2009 Jul;21(7):1321-31
pubmed: 18752414
Neurol Sci. 2008 Sep;29(4):219-27
pubmed: 18810595
Neuropsychologia. 2009 Jul;47(8-9):1917-27
pubmed: 19428424
Cogn Emot. 2009 Feb 1;23(2):209-237
pubmed: 19809584
J Psychiatry Neurosci. 2009 Nov;34(6):418-32
pubmed: 19949718
J Med Phys. 2009 Jan;34(1):37-42
pubmed: 20126564
Neuropsychology. 2010 Mar;24(2):176-91
pubmed: 20230112
Neuropsychol Rev. 2010 Jun;20(2):191-208
pubmed: 20383586
Mov Disord. 2010 Jul 15;25(9):1190-4
pubmed: 20629138
Cortex. 2011 Jul-Aug;47(7):880-4
pubmed: 21429482
Biol Psychiatry. 2011 Jun 15;69(12):e113-25
pubmed: 21531388
Exp Neurol. 2012 Jan;233(1):253-63
pubmed: 22056940
Mov Disord. 2012 Feb;27(2):186-99
pubmed: 22162004
Neuropsychologia. 2012 Jul;50(8):2121-8
pubmed: 22640663
J Int Neuropsychol Soc. 2014 May;20(5):496-505
pubmed: 24713515
Neuroscience. 2015 Mar 12;288:94-104
pubmed: 25522721
PLoS One. 2015 Aug 18;10(8):e0136110
pubmed: 26285212
Neurosci Lett. 2015 Nov 16;609:142-6
pubmed: 26497912
Behav Brain Res. 2016 Feb 1;298(Pt B):248-60
pubmed: 26515932
Nutr Neurosci. 2017 Nov;20(9):505-512
pubmed: 27276372
J Integr Neurosci. 2016 Jun;15(2):191-203
pubmed: 27301905
Behav Neurol. 2016;2016:9287092
pubmed: 27555668
PLoS One. 2017 Jan 9;12(1):e0169110
pubmed: 28068393
Ann Neurosci. 2017 May;24(2):82-89
pubmed: 28588363
Arch Neurol. 1985 Oct;42(10):943-50
pubmed: 4038101
Exp Neurol. 1973 Mar-Apr;39(2):204-14
pubmed: 4634005
Neurology. 1967 May;17(5):427-42
pubmed: 6067254
J Neurol Neurosurg Psychiatry. 1984 Aug;47(8):840-3
pubmed: 6470725
Neurology. 1995 Sep;45(9):1696-702
pubmed: 7675229
J Neurosci. 1996 Dec 1;16(23):7678-87
pubmed: 8922424
Neuroimage. 1996 Dec;4(3 Pt 1):194-200
pubmed: 9345509
Neuropsychology. 1998 Apr;12(2):253-8
pubmed: 9556771
Trends Neurosci. 1998 May;21(5):188-94
pubmed: 9610880
Brain. 1998 May;121 ( Pt 5):949-65
pubmed: 9619196
Brain Cogn. 1998 Oct;38(1):36-52
pubmed: 9735177
J Clin Exp Neuropsychol. 1998 Jun;20(3):320-7
pubmed: 9845159