Multiplex assay for multiomics advances in personalized-precision medicine.


Journal

Journal of immunoassay & immunochemistry
ISSN: 1532-4230
Titre abrégé: J Immunoassay Immunochem
Pays: England
ID NLM: 100963688

Informations de publication

Date de publication:
2019
Historique:
pubmed: 12 1 2019
medline: 1 3 2019
entrez: 12 1 2019
Statut: ppublish

Résumé

Building the future of precision medicine is the main focus in cancer domain. Clinical trials are moving toward an array of studies that are more adapted to precision medicine. In this domain, there is an enhanced need for biomarkers, monitoring devices, and data-analysis methods. Omics profiling using whole genome, epigenome, transcriptome, proteome, and metabolome can offer detailed information of the human body in an integrative manner. Omes profiles reflect more accurately real-time physiological status. Personalized omics analyses both disease as a whole and the main disease processes, for a better understanding of the individualized health. Through this, multi-omic approaches for health monitoring, preventative medicine, and personalized treatment can be targeted simultaneously and can lead clinicians to have a comprehensive view on the diseasome.

Identifiants

pubmed: 30632882
doi: 10.1080/15321819.2018.1562940
doi:

Substances chimiques

Biomarkers 0
Proteome 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3-25

Auteurs

Maria-Linda Popa (ML)

a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
b Cellular and Molecular Biology and Histology Department , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

Radu Albulescu (R)

a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
c Pharmaceutical Biotechnology Department , National Institute for Chemical-Pharmaceutical R&D , Bucharest , Romania.

Monica Neagu (M)

a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
d Faculty of Biology , University of Bucharest , Bucharest , Romania.

Mihail Eugen Hinescu (ME)

a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
b Cellular and Molecular Biology and Histology Department , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

Cristiana Tanase (C)

a Biochemistry-Proteomics Department , Victor Babes National Institute of Pathology , Bucharest , Romania.
e Cajal Institute , Titu Maiorescu University , Bucharest , Romania.

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Classifications MeSH