Neurological Disorders in Central Spain, Second Survey: Feasibility Pilot Observational Study.
NEDICES
Parkinson’s disease
dementia
essential tremor
headache
longitudinal study
mild cognitive impairment
observational study
pilot study
population-based study
stroke
Journal
JMIR research protocols
ISSN: 1929-0748
Titre abrégé: JMIR Res Protoc
Pays: Canada
ID NLM: 101599504
Informations de publication
Date de publication:
10 Jan 2019
10 Jan 2019
Historique:
received:
02
05
2018
accepted:
17
07
2018
revised:
16
07
2018
entrez:
12
1
2019
pubmed:
12
1
2019
medline:
12
1
2019
Statut:
epublish
Résumé
The Neurological Disorders in Central Spain, second survey (NEDICES-2) is a population-based, closed-cohort study that will include over 8000 subjects aged ≥55 years. It will also include a biobank. The objective of this study was to evaluate all major aspects of the NEDICES-2 (methods, database, screening instruments, and questionnaires, as well as interexpert rating of the neurological diagnoses) in each one of the planned areas (all of them in central Spain) and to test the possibility of obtaining biological samples from each participant. A selection of patients and participants of the planned NEDICES-2 underwent face-to-face interviews including a comprehensive questionnaire on demographics, current medications, medical conditions, and lifestyle habits. Biological samples (blood, saliva, urine, and hair) were also obtained. Furthermore, every participant was examined by a neurologist. In this pilot study, 567 study participants were enrolled (196 from hospitals and 371 from primary care physician lists). Of these 567, 310 completed all study procedures (questionnaires and the neurological evaluation). The study was time-consuming for several primary care physicians. Hence, a few primary care physicians from some areas refused to participate, which led to a reconfiguration of study areas. In addition, the central biobank needed to be supplemented by the biobanks of local Spanish National Health System hospitals. Population-based epidemiological surveys, such as the NEDICES-2, require a pilot study to evaluate the feasibility of all aspects of a future field study (population selection, methods and instruments to be used, neurological diagnosis agreement, and data collection).
Sections du résumé
BACKGROUND
BACKGROUND
The Neurological Disorders in Central Spain, second survey (NEDICES-2) is a population-based, closed-cohort study that will include over 8000 subjects aged ≥55 years. It will also include a biobank.
OBJECTIVE
OBJECTIVE
The objective of this study was to evaluate all major aspects of the NEDICES-2 (methods, database, screening instruments, and questionnaires, as well as interexpert rating of the neurological diagnoses) in each one of the planned areas (all of them in central Spain) and to test the possibility of obtaining biological samples from each participant.
METHODS
METHODS
A selection of patients and participants of the planned NEDICES-2 underwent face-to-face interviews including a comprehensive questionnaire on demographics, current medications, medical conditions, and lifestyle habits. Biological samples (blood, saliva, urine, and hair) were also obtained. Furthermore, every participant was examined by a neurologist.
RESULTS
RESULTS
In this pilot study, 567 study participants were enrolled (196 from hospitals and 371 from primary care physician lists). Of these 567, 310 completed all study procedures (questionnaires and the neurological evaluation). The study was time-consuming for several primary care physicians. Hence, a few primary care physicians from some areas refused to participate, which led to a reconfiguration of study areas. In addition, the central biobank needed to be supplemented by the biobanks of local Spanish National Health System hospitals.
CONCLUSIONS
CONCLUSIONS
Population-based epidemiological surveys, such as the NEDICES-2, require a pilot study to evaluate the feasibility of all aspects of a future field study (population selection, methods and instruments to be used, neurological diagnosis agreement, and data collection).
Identifiants
pubmed: 30632964
pii: v8i1e10941
doi: 10.2196/10941
pmc: PMC6329894
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e10941Informations de copyright
©Jesús Hernández-Gallego, Sara Llamas-Velasco, Felix Bermejo-Pareja, Saturio Vega, Ester Tapias-Merino, Emiliano Rodríguez-Sánchez, Elina Boycheva, José Ignacio Serrano, Juan-Francisco Gil-García, Rocio Trincado, José-María Vizcaino Sánchez-Rodrigo, Jesús Cacho, Israel Contador, Sara Garcia-Ptacek, Fernando Sierra-Hidalgo, Esther Cubo, Eva Carro, Alberto Villarejo-Galende, Rosalía García García-Patino, Julián Benito-León. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 10.01.2019.
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