Adaptation of visual cortex to damage of visual pathways in suprasellar tumors before and after gamma knife radiosurgery.
Adaptation, Physiological
Adolescent
Adult
Aged
Brain Neoplasms
/ diagnostic imaging
Child
Female
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neuronal Plasticity
Organ Size
Radiosurgery
Retrospective Studies
Treatment Outcome
Vision Disorders
/ diagnostic imaging
Visual Cortex
/ diagnostic imaging
Visual Fields
/ physiology
Visual Pathways
/ diagnostic imaging
Young Adult
Gamma knife radiosurgery
Neuroplasticity
Suprasellar tumors
Visual cortex
Journal
Journal of neuro-oncology
ISSN: 1573-7373
Titre abrégé: J Neurooncol
Pays: United States
ID NLM: 8309335
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
08
11
2018
accepted:
05
01
2019
pubmed:
15
1
2019
medline:
20
8
2019
entrez:
15
1
2019
Statut:
ppublish
Résumé
To demonstrate that lesions of the visual pathways due to suprasellar tumors are accompanied by alterations of the visual cortex and to see if these alterations are reversible after treatment of tumors by gamma knife radiosurgery. In 36 patients with peri-optic tumors and defects of their visual fields and in an age-matched control group, magnetic resonance imaging was performed before and after treatment. T1 weighted images were evaluated by voxel-based morphometry and correlated to the degree of visual field defects. In patients, grey matter density and cortical thickness were reduced in all parts of the occipital cortex, reaching significance (p < 0.05) in the left superior and middle occipital gyri, with correlation to visual field defects. Follow-up scans showed further reduction in all occipital areas. As in other peripheral lesions of the optic system, damage of the optic pathways affects the visual cortex. A prospective follow-up study is needed to determine if these alterations are reversible after successful tumor treatment.
Identifiants
pubmed: 30637609
doi: 10.1007/s11060-019-03092-4
pii: 10.1007/s11060-019-03092-4
doi:
Types de publication
Journal Article
Langues
eng
Pagination
275-282Références
Ann N Y Acad Sci. 2003 Nov;999:514-7
pubmed: 14681175
Nat Rev Neurosci. 2004 Jan;5(1):24-34
pubmed: 14708001
Hum Brain Mapp. 2005 Jun;25(2):222-36
pubmed: 15846772
Vis Neurosci. 2005 Mar-Apr;22(2):187-201
pubmed: 15935111
Br J Ophthalmol. 2006 Jun;90(6):674-8
pubmed: 16464969
Neuroimage. 2006 Jul 1;31(3):968-80
pubmed: 16530430
Neuroimage. 2008 Feb 1;39(3):1064-80
pubmed: 18037310
Brain. 2009 Jul;132(Pt 7):1898-906
pubmed: 19467992
Int J Radiat Biol. 2010 Jun;86(6):486-98
pubmed: 20470198
Hum Brain Mapp. 2010 Dec;31(12):1900-6
pubmed: 20827728
Cereb Cortex. 2012 Apr;22(4):865-76
pubmed: 21709176
Acta Ophthalmol. 2013 Feb;91(1):58-65
pubmed: 22103594
Neuron. 2012 Jul 26;75(2):250-64
pubmed: 22841310
Neuroimage. 2013 Jan 15;65:336-48
pubmed: 23041529
Cortex. 2014 Jul;56:99-110
pubmed: 23453791
Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5880-7
pubmed: 23838767
Eur J Neurosci. 2013 Nov;38(10):3456-64
pubmed: 24033706
JAMA Ophthalmol. 2014 Jan;132(1):63-8
pubmed: 24232933
Cereb Cortex. 2015 Aug;25(8):2035-48
pubmed: 24518755
Brain. 2014 Apr;137(Pt 4):1224-40
pubmed: 24648057
PLoS One. 2014 Aug 27;9(8):e105931
pubmed: 25162716
PLoS One. 2016 Jan 20;11(1):e0146684
pubmed: 26789126
Sci Rep. 2016 Mar 24;6:23268
pubmed: 27009536
Ophthalmic Physiol Opt. 2016 May;36(3):240-65
pubmed: 27112223
Curr Neurol Neurosci Rep. 2016 Oct;16(10):89
pubmed: 27542799
J Neurosci. 2017 May 17;37(20):5065-5073
pubmed: 28432144
AJNR Am J Neuroradiol. 1997 Aug;18(7):1291-5
pubmed: 9282857
J Neurol Neurosurg Psychiatry. 1998 Dec;65(6):870-6
pubmed: 9854963