Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from nerve agents.

Assistance and protection against chemical weapons Chemical Weapons Convention Chemical warfare agent Medical countermeasures Nerve agent The Organisation for the Prohibition of Chemical Weapons

Journal

Toxicology
ISSN: 1879-3185
Titre abrégé: Toxicology
Pays: Ireland
ID NLM: 0361055

Informations de publication

Date de publication:
01 03 2019
Historique:
received: 01 09 2018
revised: 04 01 2019
accepted: 07 01 2019
pubmed: 15 1 2019
medline: 29 10 2019
entrez: 15 1 2019
Statut: ppublish

Résumé

The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice on assistance and protection in relation to the Chemical Weapons Convention. In this, the first of several papers describing the SAB's work on this topic, we describe advice given in response to questions from the OPCW Director-General in 2013 and 2014 on the status of available medical countermeasures and treatments to organophosphorus nerve agents. This paper provides the evidence base for this advice which recommended to the OPCW pretreatments, emergency care, and long-term treatments that were available at the time of the request for this class of chemical warfare agent (CWA). It includes a bibliography of over 140 scientific references, which can be used as a platform for watching future medical countermeasure developments. The information provided in this paper should serve as a valuable reference for medical professionals and emergency responders who may have no knowledge of the symptoms and treatment options of exposure to nerve agents.

Identifiants

pubmed: 30639304
pii: S0300-483X(19)30011-3
doi: 10.1016/j.tox.2019.01.004
pii:
doi:

Substances chimiques

Chemical Warfare Agents 0
Nerve Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

56-69

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Christopher M Timperley (CM)

Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom. Electronic address: cmtimperley@dstl.gov.uk.

Jonathan E Forman (JE)

OPCW Scientific Advisory Board Secretary and Science Policy Adviser, The Organisation for the Prohibition of Chemical Weapons (OPCW), The Hague, The Netherlands. Electronic address: jonathan.forman@opcw.org.

Mohammad Abdollahi (M)

Toxicology and Diseases Group, The Institute of Pharmaceutical Sciences (TIPS), and Department of Toxicology and Pharmacology, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.

Abdullah Saeed Al-Amri (AS)

Saudi Basic Industries Corporation (SABIC), Riyadh, Saudi Arabia.

Augustin Baulig (A)

Secrétariat Général de la Défense et de la Sécurité Nationale (SGDSN), Paris, France.

Djafer Benachour (D)

LMPMP, Faculty of Technology, Ferhat Abbas University, Setif-1, Algeria.

Veronica Borrett (V)

BAI Scientific, Melbourne, Australia; University of Melbourne, Melbourne, Australia.

Flerida A Cariño (FA)

University of the Philippines, Quezon City, Philippines.

Michael Geist (M)

BASF SE, Ludwigshafen, Germany.

David Gonzalez (D)

Facultad de Química, Universidad de la República, Montevideo, Uruguay.

William Kane (W)

Monsanto Company, Louisiana, United States.

Zrinka Kovarik (Z)

Institute for Medical Research and Occupational Health, Zagreb, Croatia.

Roberto Martínez-Álvarez (R)

Complutense University, Madrid, Spain.

Nicia Maria Fusaro Mourão (NMF)

ABIQUIM, Brazilian Chemical Industry Association, São Paulo, Brazil.

Slawomir Neffe (S)

Military University of Technology, Warsaw, Poland.

Syed K Raza (SK)

Institute of Pesticides Formulation Technology (IPFT), Gurugram, Haryana, India.

Valentin Rubaylo (V)

State Scientific Research Institute of Organic Chemistry and Technology (GosNIIOKhT), Moscow, Russian Federation.

Alejandra Graciela Suárez (AG)

Universidad Nacional de Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas, Rosario, Argentina.

Koji Takeuchi (K)

National Institute of Advanced Industrial Science and Technology (AIST), Japan.

Cheng Tang (C)

Office for the Disposal of Japanese Abandoned Chemical Weapons, Ministry of National Defence, Beijing, China.

Ferruccio Trifirò (F)

Department of Industrial Chemistry, University of Bologna, Bologna, Italy.

Francois Mauritz van Straten (FM)

South African Nuclear Energy Corporation SOC Ltd., Pretoria, South Africa.

Paula S Vanninen (PS)

VERIFIN, Department of Chemistry, Faculty of Science, University of Helsinki, Helsinki, Finland.

Slavica Vučinić (S)

National Poison Control Centre, Military Medical Academy, Belgrade, Serbia.

Volodymyr Zaitsev (V)

Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; Pontifical Catholic University of Rio de Janeiro, Brazil.

Muhammad Zafar-Uz-Zaman (M)

National Engineering and Scientific Commission (NESCOM), Islamabad, Pakistan.

Mongia Saïd Zina (MS)

Faculty of Sciences of Tunis (FST), Tunis, Tunisia.

Stian Holen (S)

OPCW Scientific Advisory Board Secretary, 2011-2016, The Netherlands.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH