Pro- and anti-oxidant properties of near-infrared (NIR) light responsive carbon nanoparticles.


Journal

Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159

Informations de publication

Date de publication:
04 2019
Historique:
received: 10 10 2018
revised: 27 12 2018
accepted: 08 01 2019
pubmed: 15 1 2019
medline: 27 3 2020
entrez: 15 1 2019
Statut: ppublish

Résumé

Elemental carbon nanomaterials (ECNMs) are redox active agents that can be exploited to purposely modify the redox balance of cells. Both pro- or antioxidant properties have been reported. However, to the best of our knowledge, there are not comprehensive studies exploring both properties on the same material in view of a potential application in medicine. At the same time, the effect of the bulk structure on the pro/antioxidant properties is poorly known. Here, carbon nanoparticles (CNPs) derived by glucose with definite size and shape have been prepared, and their redox properties evaluated in cell free systems in the dark or following activation with a Near Infrared (NIR) laser beam (945 nm, 1.3 W/cm

Identifiants

pubmed: 30639569
pii: S0891-5849(18)32199-3
doi: 10.1016/j.freeradbiomed.2019.01.013
pii:
doi:

Substances chimiques

Antioxidants 0
Oxidants 0
Carbon 7440-44-0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

165-176

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Ida Kokalari (I)

Department of Chemistry, University of Torino, 10125 Torino, Italy.

Riccardo Gassino (R)

Department of Electronics and Telecommunications, Politecnico di Torino, 10129 Torino, Italy.

Andrea M Giovannozzi (AM)

National Institute of Metrological Research (INRiM), 10135 Torino, Italy.

Luca Croin (L)

National Institute of Metrological Research (INRiM), 10135 Torino, Italy.

Elena Gazzano (E)

Department of Oncology, University of Torino, 10126 Torino, Italy.

Enrico Bergamaschi (E)

Department of Public Health and Pediatrics, University of Torino, 10126 Torino, Italy.

Andrea M Rossi (AM)

National Institute of Metrological Research (INRiM), 10135 Torino, Italy.

Guido Perrone (G)

Department of Electronics and Telecommunications, Politecnico di Torino, 10129 Torino, Italy.

Chiara Riganti (C)

Department of Oncology, University of Torino, 10126 Torino, Italy.

Jessica Ponti (J)

Directorate F - Health, Consumers and Reference Materials Consumer Products Safety Unit (F.2), JRC, Ispra (Va), Italy.

Ivana Fenoglio (I)

Department of Chemistry, University of Torino, 10125 Torino, Italy. Electronic address: ivana.fenoglio@unito.it.

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Classifications MeSH