Health-Related Quality of Life of Pediatric Spinal Surgery Complications.
HRQOL
acetazolamide side effects
spinal surgery complications
utility
visual analogue scale (VAS)
Journal
Value in health regional issues
ISSN: 2212-1102
Titre abrégé: Value Health Reg Issues
Pays: United States
ID NLM: 101592642
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
21
06
2018
revised:
09
11
2018
accepted:
27
11
2018
pubmed:
15
1
2019
medline:
6
8
2019
entrez:
15
1
2019
Statut:
ppublish
Résumé
Health-related quality of life (utility) measures are essential components of effectiveness analyses. The health-related quality of life of health states in pediatric patients who underwent spinal surgery have not been reported previously. To estimate the utility of complications after spinal surgeries and side effects of acetazolamide administration. Parent caregivers, nurses, neurosurgeons, and orthopedists were interviewed as proxies to evaluate the preference of health conditions in pediatric patients who underwent intradural surgeries. We measured the utility of spinal surgery complications (cerebrospinal fluid leakage and collection, wound dehiscence, operation site infection, and secondary repair of operation site), side effects of acetazolamide administration (loss of appetite, mild gastroenteritis, and severe acid/base and/or electrolyte imbalance), taking pills (for 10 days, 1 month, and 1 year), and 24 hours of ward or intensive care unit admission by visual analogue scale. One hundred individuals were interviewed (pilot study: 20 individuals; main study: 40 parents, 27 nurses, 8 neurosurgeons, and 5 orthopedists). Sixty-four (80%) of the respondents were female. Taking pills for 10 days had the highest utility value (0.71 ± 0.13), whereas secondary surgical repair of the operation site and acid/base and/or electrolyte imbalance had the lowest preference (0.19 ± 0.16 and 0.23 ± 0.11, respectively). This study provides the utility measures for quality assessment of temporary postsurgical events in pediatric patients.
Sections du résumé
BACKGROUND
BACKGROUND
Health-related quality of life (utility) measures are essential components of effectiveness analyses. The health-related quality of life of health states in pediatric patients who underwent spinal surgery have not been reported previously.
OBJECTIVES
OBJECTIVE
To estimate the utility of complications after spinal surgeries and side effects of acetazolamide administration.
METHODS
METHODS
Parent caregivers, nurses, neurosurgeons, and orthopedists were interviewed as proxies to evaluate the preference of health conditions in pediatric patients who underwent intradural surgeries. We measured the utility of spinal surgery complications (cerebrospinal fluid leakage and collection, wound dehiscence, operation site infection, and secondary repair of operation site), side effects of acetazolamide administration (loss of appetite, mild gastroenteritis, and severe acid/base and/or electrolyte imbalance), taking pills (for 10 days, 1 month, and 1 year), and 24 hours of ward or intensive care unit admission by visual analogue scale.
RESULTS
RESULTS
One hundred individuals were interviewed (pilot study: 20 individuals; main study: 40 parents, 27 nurses, 8 neurosurgeons, and 5 orthopedists). Sixty-four (80%) of the respondents were female. Taking pills for 10 days had the highest utility value (0.71 ± 0.13), whereas secondary surgical repair of the operation site and acid/base and/or electrolyte imbalance had the lowest preference (0.19 ± 0.16 and 0.23 ± 0.11, respectively).
CONCLUSIONS
CONCLUSIONS
This study provides the utility measures for quality assessment of temporary postsurgical events in pediatric patients.
Identifiants
pubmed: 30639949
pii: S2212-1099(18)30375-3
doi: 10.1016/j.vhri.2018.11.005
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
74-77Informations de copyright
Copyright © 2018 ISPOR--The professional society for health economics and outcomes research. Published by Elsevier Inc. All rights reserved.