Difluorocarbene-derived trifluoromethylselenolation of benzyl halides.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
29 Jan 2019
29 Jan 2019
Historique:
pubmed:
15
1
2019
medline:
15
1
2019
entrez:
15
1
2019
Statut:
ppublish
Résumé
Cu-Promoted difluorocarbene-derived trifluoromethylselenolation of benzyl halides with the Ph3P+CF2CO2-/Se/F- system is described. Three new carbon-heteroatom bonds, a Se-CF2 bond, SeCF2-F bond, and C-SeCF3 bond, were sequentially formed in the reaction. This work represents the first trifluoromethylselenolation protocol involving an external fluoride for the generation of the key intermediate, CF3Se- anion.
Types de publication
Journal Article
Langues
eng