Immunological Responses to the Relapsing Fever Spirochete
Animals
Antibodies, Bacterial
/ immunology
Antibody Formation
Bacterial Outer Membrane Proteins
/ genetics
Borrelia
/ genetics
Disease Models, Animal
Humans
Interleukin-1beta
/ genetics
Macaca mulatta
/ microbiology
Male
Mice
Mice, Inbred ICR
Relapsing Fever
/ diagnosis
Ticks
/ microbiology
Tumor Necrosis Factor-alpha
/ genetics
Virulence
Borrelia
adaptive immunity
humoral immunity
nonhuman primate
relapsing fever
Journal
Infection and immunity
ISSN: 1098-5522
Titre abrégé: Infect Immun
Pays: United States
ID NLM: 0246127
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
19
12
2018
accepted:
07
01
2019
pubmed:
16
1
2019
medline:
29
8
2019
entrez:
16
1
2019
Statut:
epublish
Résumé
The global public health impact of relapsing fever (RF) spirochetosis is significant, since the pathogens exist on five of seven continents. The hallmark sign of infection is episodic fever and the greatest threat is to the unborn. With the goal of better understanding the specificity of B-cell responses and the role of immune responses in pathogenicity, we infected rhesus macaques with
Identifiants
pubmed: 30642902
pii: IAI.00900-18
doi: 10.1128/IAI.00900-18
pmc: PMC6434134
pii:
doi:
Substances chimiques
Antibodies, Bacterial
0
Bacterial Outer Membrane Proteins
0
BipA protein, Bordetella
0
Interleukin-1beta
0
Tumor Necrosis Factor-alpha
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : K22 AI091652
Pays : United States
Organisme : NIH HHS
ID : P51 OD011104
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI103724
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Microbiology.
Références
PLoS One. 2016 Feb 04;11(2):e0147707
pubmed: 26845332
J Immunol. 2007 Oct 15;179(8):5109-16
pubmed: 17911596
PLoS One. 2011 Jan 27;6(1):e16524
pubmed: 21304587
J Immunol. 2001 Sep 15;167(6):3029-32
pubmed: 11544285
Infect Immun. 1984 Sep;45(3):572-6
pubmed: 6332075
J Infect Dis. 2006 Nov 15;194(10):1367-74
pubmed: 17054065
J Immunol. 2016 Feb 1;196(3):1060-9
pubmed: 26740107
Ticks Tick Borne Dis. 2017 Aug;8(5):677-681
pubmed: 28501504
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12
pubmed: 23401516
PLoS Negl Trop Dis. 2014 Apr 03;8(4):e2767
pubmed: 24699275
Infect Immun. 2010 May;78(5):1924-30
pubmed: 20145098
J Clin Microbiol. 2002 Apr;40(4):1558-62
pubmed: 11923397
FEMS Microbiol Lett. 1995 Dec 15;134(2-3):255-8
pubmed: 8586277
Vet Sci. 2016 Aug 30;3(3):
pubmed: 29056727
J Clin Microbiol. 2005 Aug;43(8):3851-9
pubmed: 16081922
East Afr Med J. 1991 Nov;68(11):875-9
pubmed: 1800081
J Pathol. 1980 Feb;130(2):83-90
pubmed: 7365574
J Immunol. 2001 Nov 15;167(10):5669-77
pubmed: 11698439
J Exp Med. 1992 May 1;175(5):1207-12
pubmed: 1569394
J Med Microbiol. 1997 Aug;46(8):675-80
pubmed: 9511816
Mediators Inflamm. 2006;2006(4):30485
pubmed: 17047289
JAMA. 1969 Apr 28;208(4):690-2
pubmed: 5818572
Clin Immunol. 2011 Sep;140(3):223-8
pubmed: 21622026
Emerg Infect Dis. 2007 Jan;13(1):117-23
pubmed: 17370524
Infect Dis Clin North Am. 2008 Sep;22(3):449-68, viii
pubmed: 18755384
Infect Immun. 2001 Feb;69(2):1009-15
pubmed: 11159997
East Afr Med J. 1987 Apr;64(4):284-6
pubmed: 3691349
Clin Vaccine Immunol. 2010 Apr;17(4):564-71
pubmed: 20147497
PLoS Negl Trop Dis. 2013 Oct 31;7(10):e2514
pubmed: 24205425
Cytometry A. 2015 Sep;87(9):800-2
pubmed: 26115002
Eur J Immunol. 2006 Mar;36(3):583-92
pubmed: 16506292
Acta Obstet Gynecol Scand. 1997 Oct;76(9):834-8
pubmed: 9351408
Cytometry B Clin Cytom. 2010;78 Suppl 1:S47-60
pubmed: 20839338
East Afr Med J. 1991 Dec;68(12):999-1005
pubmed: 1800101
Lancet Infect Dis. 2003 Oct;3(10):604
pubmed: 14558501
J Immunol. 2009 Jan 1;182(1):498-506
pubmed: 19109181
Trop Geogr Med. 1987 Jan;39(1):92-3
pubmed: 3603698
Trans R Soc Trop Med Hyg. 1990 Nov-Dec;84(6):852-6
pubmed: 2096523
Pharmacol Rev. 1957 Dec;9(4):427-79
pubmed: 13517946
Br J Obstet Gynaecol. 1988 Oct;95(10):1070-2
pubmed: 3191046
Virol J. 2012 Aug 13;9:160
pubmed: 22889373
PLoS One. 2012;7(12):e51914
pubmed: 23251652
Science. 1939 Sep 22;90(2334):275-6
pubmed: 17774199
J Clin Microbiol. 1996 Oct;34(10):2483-92
pubmed: 8880505
PLoS Negl Trop Dis. 2013 Sep 19;7(9):e2454
pubmed: 24069498
Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6293-8
pubmed: 16606838
Parasit Vectors. 2015 Oct 21;8:546
pubmed: 26490040
Med Clin North Am. 2002 Mar;86(2):417-33, viii-ix
pubmed: 11982310
Infect Immun. 1999 Dec;67(12):6702-6
pubmed: 10569796
Immunol Rev. 2007 Oct;219:157-66
pubmed: 17850488
Curr Opin Infect Dis. 2009 Oct;22(5):443-9
pubmed: 19623064
Int J Biochem Cell Biol. 2011 Mar;43(3):280-5
pubmed: 21147251
Trop Doct. 2013 Oct;43(4):138-41
pubmed: 23976777
J Immunol. 2013 Apr 1;190(7):3100-8
pubmed: 23455507
Acta Obstet Gynecol Scand. 1997 Mar;76(3):205-11
pubmed: 9093132
Physiol Behav. 1992 Dec;52(6):1133-9
pubmed: 1484872
Lab Invest. 1956 May-Jun;5(3):283-94
pubmed: 13320788
Immunology. 2009 Nov;128(3):311-23
pubmed: 20067531
Science. 1998 Jun 19;280(5371):1938-40
pubmed: 9632392
Am J Obstet Gynecol. 2006 Dec;195(6):1578-89
pubmed: 17132473
J Immunol. 2003 Apr 1;170(7):3819-27
pubmed: 12646649
Immunity. 2004 Sep;21(3):379-90
pubmed: 15357949
J Infect Dis. 2014 Nov 15;210(10):1639-48
pubmed: 24879799