The neurobiology of addiction.
addiction
alcohol
marijuana
neuroplasticity
nicotine
opioids
substance abuse
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
26
09
2018
accepted:
22
10
2018
pubmed:
16
1
2019
medline:
9
4
2020
entrez:
16
1
2019
Statut:
ppublish
Résumé
Substance and alcohol use disorders impose large health and economic burdens on individuals, families, communities, and society. Neither prevention nor treatment efforts are effective in all individuals. Results are often modest. Advances in neuroscience and addiction research have helped to describe the neurobiological changes that occur when a person transitions from recreational substance use to a substance use disorder or addiction. Understanding both the drivers and consequences of substance use in vulnerable populations, including those whose brains are still maturing, has revealed behavioral and biological characteristics that can increase risks of addiction. These findings are particularly timely, as law- and policymakers are tasked to reverse the ongoing opioid epidemic, as more states legalize marijuana, as new products including electronic cigarettes and newly designed abused substances enter the legal and illegal markets, and as "deaths of despair" from alcohol and drug misuse continue.
Identifiants
pubmed: 30644552
doi: 10.1111/nyas.13989
pmc: PMC6767400
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
5-28Subventions
Organisme : NIDA NIH HHS
ID : R13 DA041813
Pays : United States
Informations de copyright
© 2019 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of The New York Academy of Sciences.
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