Low-grade infections as a possible cause of arthrofibrosis after total knee arthroplasty.
Arthrofibrosis
PCR
Total knee arthroplasty
Journal
Patient safety in surgery
ISSN: 1754-9493
Titre abrégé: Patient Saf Surg
Pays: England
ID NLM: 101319176
Informations de publication
Date de publication:
2019
2019
Historique:
received:
07
09
2018
accepted:
11
12
2018
entrez:
17
1
2019
pubmed:
17
1
2019
medline:
17
1
2019
Statut:
epublish
Résumé
Arthrofibrosis after total knee arthroplasty represents a considerable burden for the patient and a therapeutic challenge for the practitioner. One possible cause discussed in the literature is a low-grade infection. This hypothesis should be examined within the scope of this retrospective study. Nineteen patients with clinical symptoms of arthrofibrosis after primary total knee arthroplasty were examined between January, 1999 and January, 2012. Incorrect positioning was radiologically ruled out. All patients were examined clinically (score of Freeman as well as Blauth and Jäger), radiologically (component and leg alignment, patella height according to Insall and Salvati), microbiologically (culture-based procedures), molecular biologically (PCR) and histologically in the course of an open revision of the prosthesis. According to the score of Freeman et al. (1977), a highly significant improvement in pain ( The hypothesis of low-grade-infection-induced arthrofibrosis after total knee arthroplasty could not be confirmed in this study. However, based on this small study population the conclusion needs to be confirmed by new and larger studies, ideally prospectively designed including a control group.
Identifiants
pubmed: 30647774
doi: 10.1186/s13037-018-0181-1
pii: 181
pmc: PMC6327456
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1Déclaration de conflit d'intérêts
The ethics committee of the University Hospital Jena in Germany granted ethical approval (ref. no. 3409–03/12). The committee is listed in the Institutional Review Board (IRB) of the Office for Human Research Protections (OHRP) IORG0003487, IRB00004153.All authors declare no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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