Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy.
hepatocellular carcinoma
prealbumin
prognosis
Journal
Journal of surgical oncology
ISSN: 1096-9098
Titre abrégé: J Surg Oncol
Pays: United States
ID NLM: 0222643
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
24
10
2018
accepted:
30
12
2018
pubmed:
17
1
2019
medline:
18
4
2019
entrez:
17
1
2019
Statut:
ppublish
Résumé
To determine whether serum prealbumin levels are associated with long-term survival after hepatectomy in patients with primary hepatocellular carcinoma(HCC). A consecutive sample of 526 patients with HCC who underwent potentially curative hepatectomy from August 2007 to August 2010 was retrospectively analyzed. Patients were classified as having normal or reduced serum prealbumin based on cut-off values of 200 or 182 mg/L. Multivariate analysis identified the preoperative level of serum prealbumin as an independent prognostic factor of long-term survival (P < 0.05): Survival was significantly better for those with normal levels than for those with reduced levels, based on either cut-off value. Similar results were observed in subgroup analyses based on the degree of cirrhosis, level of ɑ-fetoprotein and Barcelona Clinic Liver Cancer stage. Preoperative level of serum prealbumin may be useful for predicting long-term survival in patients with HCC after hepatectomy.
Substances chimiques
Biomarkers
0
Prealbumin
0
alpha-Fetoproteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
794-800Subventions
Organisme : Guangxi University of Science and Technology Research Projects
ID : KY2015LX056
Organisme : Self-Raised Scientific Research Fund of the Ministry of Health of Guangxi Province
ID : GZZC15-34
Organisme : Self-Raised Scientific Research Fund of the Ministry of Health of Guangxi Province
ID : Z2015621
Organisme : Self-Raised Scientific Research Fund of the Ministry of Health of Guangxi Province
ID : Z2016512
Organisme : Self-Raised Scientific Research Fund of the Ministry of Health of Guangxi Province
ID : Z2016479
Organisme : Graduate Course Construction Project of Guangxi Medical University
ID : YJSA2017014
Organisme : Foundation Ability Enhancement Project for Young Teachers in Guangxi Universities
ID : 2018KY0122
Organisme : Guangxi Natural Science Foundation
ID : 2018GXNSFBA138018
Organisme : National Science Fund Subsidized Project, Grant/Award Number: 81060173
Organisme : Innovation Project of Guangxi Graduate Education
ID : YCSW2018107
Organisme : Medical and Health Care Appropriate Technology Research and Development Projects of Guangxi Province
ID : S201417
Organisme : Medical and Health Care Appropriate Technology Research and Development Projects of Guangxi Province
ID : S201417-01
Informations de copyright
© 2019 Wiley Periodicals, Inc.