Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.
cancer-associated fibroblasts
innate immunity
tumor microenvironment
Journal
Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691
Informations de publication
Date de publication:
15 01 2019
15 01 2019
Historique:
received:
31
08
2018
revised:
05
11
2018
accepted:
17
12
2018
entrez:
17
1
2019
pubmed:
17
1
2019
medline:
10
4
2020
Statut:
ppublish
Résumé
MyD88, an adaptor molecule downstream of innate pathways, plays a significant tumor-promoting role in sporadic intestinal carcinogenesis of the Apc
Identifiants
pubmed: 30650348
pii: S2211-1247(18)32017-5
doi: 10.1016/j.celrep.2018.12.072
pmc: PMC6334226
pii:
doi:
Substances chimiques
Myeloid Differentiation Factor 88
0
Tlr4 protein, mouse
0
Toll-Like Receptor 4
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
536-545.e4Informations de copyright
Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.
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