Risk Factors and Outcomes of Recurrent Candidemia in Children: Relapse or Re-Infection?
antifungal resistance
late-onset sepsis
premature infants
recurrent candidemia
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 Jan 2019
16 Jan 2019
Historique:
received:
14
12
2018
revised:
07
01
2019
accepted:
11
01
2019
entrez:
19
1
2019
pubmed:
19
1
2019
medline:
19
1
2019
Statut:
epublish
Résumé
In this paper, our aim was to investigate the incidence, clinical characteristics, risk factors, and outcomes of recurrent candidemia in children. We retrospectively reviewed all children with candidemia from a medical center in Taiwan between 2004 and 2015. Two episodes of candidemia ≥30 days apart with clinical and microbiological resolution in the interim were defined as "late recurrence", and those that had 8⁻29 days apart from previous episodes were defined as "early recurrence". 45 patients (17.2%) had 57 episodes of recurrent candidemia, and 24 had 28 episodes of late recurrent candidemia. The median time between recurrences was 1.8 months (range: <1 month to 13 months). Of those, 29 had relapsed candidemia and 28 were re-infected by different Candida species (
Identifiants
pubmed: 30654524
pii: jcm8010099
doi: 10.3390/jcm8010099
pmc: PMC6352033
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Chang Gung Memorial Hospital, Linkou
ID : CMRPG3E1491
Références
Eur J Clin Microbiol Infect Dis. 2000 Aug;19(8):585-92
pubmed: 11014620
J Clin Microbiol. 2001 Apr;39(4):1258-63
pubmed: 11283038
Clin Infect Dis. 2005 Nov 1;41(9):1232-9
pubmed: 16206095
J Clin Microbiol. 2007 Mar;45(3):698-706
pubmed: 17202279
Pediatrics. 2009 May;123(5):1360-8
pubmed: 19403503
Med Mycol. 2010 Aug;48(5):757-62
pubmed: 20105100
Clin Infect Dis. 2010 Sep 1;51(5):e38-45
pubmed: 20636126
Pediatr Infect Dis J. 2011 Aug;30(8):664-8
pubmed: 21372750
Clin Microbiol Infect. 2012 Feb;18(2):195-201
pubmed: 21733031
Curr Opin Microbiol. 2011 Aug;14(4):386-91
pubmed: 21802979
Clin Microbiol Infect. 2012 Feb;18(2):E27-30
pubmed: 22181050
Pediatr Infect Dis J. 2012 Jun;31(6):557-60
pubmed: 22333703
Clin Infect Dis. 2012 May;54(9):1240-8
pubmed: 22431804
J Clin Microbiol. 2012 Sep;50(9):2846-56
pubmed: 22740712
Pediatr Infect Dis J. 2012 Dec;31(12):1252-7
pubmed: 22982980
Intensive Care Med. 2013 Dec;39(12):2188-95
pubmed: 23942859
Pediatr Infect Dis J. 2014 Feb;33(2):e40-4
pubmed: 23995591
Clin Microbiol Infect. 2014 Jul;20(7):698-705
pubmed: 24188136
Antimicrob Agents Chemother. 2014;58(4):2438-40
pubmed: 24468776
Clin Microbiol Infect. 2014 Nov;20(11):O928-35
pubmed: 24796697
Int J Antimicrob Agents. 2014 Sep;44(3):248-55
pubmed: 25108876
Clin Microbiol Infect. 2015 Oct;21(10):938-45
pubmed: 26093076
Clin Microbiol Infect. 2015 Nov;21(11):1018.e1-8
pubmed: 26148466
Front Microbiol. 2015 Aug 05;6:791
pubmed: 26300860
Clin Microbiol Infect. 2016 Feb;22(2):181-188
pubmed: 26460064
Emerg Infect Dis. 2015 Nov;21(11):1942-50
pubmed: 26488845
Clin Microbiol Infect. 2016 Mar;22(3):277.e11-20
pubmed: 26548507
Pediatrics. 2016 Apr;137(4):
pubmed: 26956103
Clin Microbiol Infect. 2016 Aug;22(8):719-24
pubmed: 27432766
Clin Microbiol Infect. 2017 Feb;23(2):117.e1-117.e8
pubmed: 27746395
Clin Microbiol Infect. 2017 Sep;23(9):672.e1-672.e11
pubmed: 28143788
Sci Rep. 2017 Apr 24;7(1):1083
pubmed: 28439070
Clin Microbiol Infect. 2018 Jul;24(7):771-777
pubmed: 29133157
Clin Microbiol Infect. 2018 Sep;24(9):1010-1015
pubmed: 29408611
mSphere. 2018 Mar 28;3(2):
pubmed: 29600282
Am J Infect Control. 2018 Dec;46(12):1387-1393
pubmed: 30100260