Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples.


Journal

Bioinformatics (Oxford, England)
ISSN: 1367-4811
Titre abrégé: Bioinformatics
Pays: England
ID NLM: 9808944

Informations de publication

Date de publication:
01 09 2019
Historique:
received: 13 07 2018
revised: 03 12 2018
accepted: 14 01 2019
pubmed: 19 1 2019
medline: 18 6 2020
entrez: 19 1 2019
Statut: ppublish

Résumé

Ordino is a web-based analysis tool for cancer genomics that allows users to flexibly rank, filter and explore genes, cell lines and tissue samples based on pre-loaded data, including The Cancer Genome Atlas, the Cancer Cell Line Encyclopedia and manually uploaded information. Interactive tabular data visualization that facilitates the user-driven prioritization process forms a core component of Ordino. Detail views of selected items complement the exploration. Findings can be stored, shared and reproduced via the integrated session management. Ordino is publicly available at https://ordino.caleydoapp.org. The source code is released at https://github.com/Caleydo/ordino under the Mozilla Public License 2.0. Supplementary data are available at Bioinformatics online.

Identifiants

pubmed: 30657871
pii: 5292316
doi: 10.1093/bioinformatics/btz009
pmc: PMC6736116
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3140-3142

Subventions

Organisme : Austrian Science Fund FWF
ID : P 27975
Pays : Austria

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press.

Références

Nature. 2012 Mar 28;483(7391):603-7
pubmed: 22460905
BMC Bioinformatics. 2012;13 Suppl 8:S2
pubmed: 22607364
IEEE Trans Vis Comput Graph. 2013 Dec;19(12):2277-86
pubmed: 24051794
Nat Methods. 2014 Sep;11(9):884-885
pubmed: 25166867
Comput Graph Forum. 2016 Jun;35(3):491-500
pubmed: 27942091
Cell. 2017 Jul 27;170(3):577-592.e10
pubmed: 28753431
Nat Genet. 2017 Dec;49(12):1779-1784
pubmed: 29083409

Auteurs

Marc Streit (M)

Institute of Computer Graphics, Johannes Kepler University Linz, Linz A-4040, Austria.
datavisyn GmbH, Linz A-4020, Austria.

Samuel Gratzl (S)

Institute of Computer Graphics, Johannes Kepler University Linz, Linz A-4040, Austria.
datavisyn GmbH, Linz A-4020, Austria.

Holger Stitz (H)

Institute of Computer Graphics, Johannes Kepler University Linz, Linz A-4040, Austria.

Andreas Wernitznig (A)

Department of Pharmacology and Translational Research, Boehringer Ingelheim RCV GmbH & Co KG, Vienna A-1121, Austria.

Thomas Zichner (T)

Department of Pharmacology and Translational Research, Boehringer Ingelheim RCV GmbH & Co KG, Vienna A-1121, Austria.

Christian Haslinger (C)

Department of Pharmacology and Translational Research, Boehringer Ingelheim RCV GmbH & Co KG, Vienna A-1121, Austria.

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Classifications MeSH