Antibacterial Activities of Lipopeptide (C
biofilm
biofilm on contact lenses
lipopeptides
ocular infections
persister cells
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Jan 2019
17 Jan 2019
Historique:
received:
11
12
2018
revised:
09
01
2019
accepted:
14
01
2019
entrez:
20
1
2019
pubmed:
20
1
2019
medline:
2
5
2019
Statut:
epublish
Résumé
The widespread use of biomaterials such as contact lenses is associated with the development of biofilm-related infections which are very difficult to manage with standard therapies. The formation of bacterial biofilms on the surface of biomaterials is associated with increased antibiotic resistance. Owing to their promising antimicrobial potential, lipopeptides are being intensively investigated as novel antimicrobials. However, due to the relatively high toxicity exhibited by numerous compounds, a lot of attention is being paid to designing new lipopeptides with optimal biological activities. The principal aim of this study was to evaluate the potential ophthalmic application of lipopeptide (C
Identifiants
pubmed: 30658481
pii: ijms20020393
doi: 10.3390/ijms20020393
pmc: PMC6358866
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Lipopeptides
0
Polystyrenes
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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