Surgical outcomes of early-stage small-cell lung cancer: single-center experience.
Adult
Aged
Carcinoma, Non-Small-Cell Lung
/ diagnostic imaging
Female
Humans
Lung Neoplasms
/ diagnostic imaging
Lymph Node Excision
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Staging
Pneumonectomy
/ adverse effects
Positron Emission Tomography Computed Tomography
Retrospective Studies
Risk Factors
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Turkey
Carcinoma
Lung neoplasms
Lymphatic metastasis
Neoplasm staging
Pneumonectomy
Survival analysis
small cell
Journal
Asian cardiovascular & thoracic annals
ISSN: 1816-5370
Titre abrégé: Asian Cardiovasc Thorac Ann
Pays: England
ID NLM: 9503417
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
pubmed:
22
1
2019
medline:
23
4
2019
entrez:
22
1
2019
Statut:
ppublish
Résumé
Small-cell lung cancer is a highly aggressive and metastatic epithelial lung malignancy. A small percentage of these tumors can be detected at an early stage and may be appropriate for surgical treatment. We analyzed the data of patients with early-stage small-cell lung cancer who underwent lobectomy and mediastinal lymph node dissection. Between January 2011 and December 2016, 26 patients with early-stage small-cell lung cancer underwent lobectomy and mediastinal lymph node dissection and were included the study. The mean age was 60.9 years and 18 (69.2%) were male. Patients with increased uptake of The most common tumor location was the right upper lobe. The diagnoses were achieved by intraoperative frozen section study in almost all patients (92.3%). Mean overall survival was 58.5 ± 6.7 months (range 45-71 months) and the 5-year survival rate was 53%. We found that a statistically significant correlation between lymph node metastasis in N1 or N2 stations and survival. There was also a significant relationship between N2 nodal metastasis and recurrence. As stated in the current guidelines, lung lobectomy and mediastinal lymph node resection should be considered in early-stage small-cell lung cancers. Survival outcomes of surgery for early-stage small-cell lung cancer are similar to the results in non-small-cell lung cancer.
Sections du résumé
BACKGROUND
BACKGROUND
Small-cell lung cancer is a highly aggressive and metastatic epithelial lung malignancy. A small percentage of these tumors can be detected at an early stage and may be appropriate for surgical treatment. We analyzed the data of patients with early-stage small-cell lung cancer who underwent lobectomy and mediastinal lymph node dissection.
METHODS
METHODS
Between January 2011 and December 2016, 26 patients with early-stage small-cell lung cancer underwent lobectomy and mediastinal lymph node dissection and were included the study. The mean age was 60.9 years and 18 (69.2%) were male. Patients with increased uptake of
RESULTS
RESULTS
The most common tumor location was the right upper lobe. The diagnoses were achieved by intraoperative frozen section study in almost all patients (92.3%). Mean overall survival was 58.5 ± 6.7 months (range 45-71 months) and the 5-year survival rate was 53%. We found that a statistically significant correlation between lymph node metastasis in N1 or N2 stations and survival. There was also a significant relationship between N2 nodal metastasis and recurrence.
CONCLUSION
CONCLUSIONS
As stated in the current guidelines, lung lobectomy and mediastinal lymph node resection should be considered in early-stage small-cell lung cancers. Survival outcomes of surgery for early-stage small-cell lung cancer are similar to the results in non-small-cell lung cancer.
Identifiants
pubmed: 30661378
doi: 10.1177/0218492319826724
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM