A systematic review with epidemiological update of male genital schistosomiasis (MGS): A call for integrated case management across the health system in sub-Saharan Africa.

Control HIV Male genital schistosomiasis Praziquantel Urogenital schistosomiasis

Journal

Parasite epidemiology and control
ISSN: 2405-6731
Titre abrégé: Parasite Epidemiol Control
Pays: Netherlands
ID NLM: 101687137

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 13 05 2018
revised: 16 10 2018
accepted: 16 10 2018
entrez: 22 1 2019
pubmed: 22 1 2019
medline: 22 1 2019
Statut: epublish

Résumé

Male genital schistosomiasis (MGS) is a gender specific manifestation of urogenital schistosomiasis (UGS) first described in 1911 by Madden in Egypt. Today, while affecting millions of men and boys worldwide, MGS receives insufficient attention, especially in sub-Saharan Africa (SSA). To provide a systematic review with an epidemiological update of MGS, we inspected both online and hardcopy resources in our appraisal. A total of 147 articles were eventually identified, only 31 articles were exclusively focused on MGS with original or targeted research. From these, we discuss pertinent clinico-pathological features of MGS, highlight the possible connection and interplay with HIV, and assess current diagnostic techniques alongside consideration of their use and application in SSA. To appreciate the burden of MGS more fully, especially in endemic areas, there is a clear need for better surveillance and longitudinal population research to investigate the best point-of-care (POC) diagnostic and its performance through time. Furthermore, to optimise individual case management, exploration of alternative praziquantel dosing regimens is needed for MGS in men with or without HIV co-infection.

Identifiants

pubmed: 30662962
doi: 10.1016/j.parepi.2018.e00077
pii: S2405-6731(18)30019-9
pii: e00077
pmc: PMC6324017
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e00077

Commentaires et corrections

Type : ErratumIn

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Auteurs

Sekeleghe Kayuni (S)

Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom.
MASM Medi Clinics Limited, Medical Aid Society of Malawi (MASM), MASM House, 22 Lower Scalter road, P.O. Box 1254, Blantyre, Malawi.

Fanuel Lampiao (F)

College of Medicine, University of Malawi, Private Bag 360, Chichiri, Blantyre 3, Malawi.

Peter Makaula (P)

Research for Health, Environment and Development (RHED), P.O. Box 345, Mangochi.

Lazarus Juziwelo (L)

National Schistosomiasis and STH Control Program, CHSU, Ministry of Health, Lilongwe. Malawi.

E James Lacourse (EJ)

Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom.

Jutta Reinhard-Rupp (J)

Merck Global Health Institute, Ares Trading S.A., Route de Crassier 15, 1262 Eysins, Switzerland.

Peter D C Leutscher (PDC)

Centre for Clinical Research, North Denmark Regional Hospital & Department of Clinical Medicine, Aalborg University, Region Nordjylland, Denmark.

J Russell Stothard (JR)

Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom.

Classifications MeSH