New

Animals Brain / metabolism Click Chemistry Humans Isotope Labeling Male Molecular Docking Simulation Organotechnetium Compounds / chemistry Piperazine / chemical synthesis Protein Conformation Radiochemistry Rats Receptor, Serotonin, 5-HT2C / chemistry Tissue Distribution
1-(2-methoxyphenyl)piperazine (MPP) 2-ethynylpyridine 5HT1A homology model WAY100635 click chemistry docking

Journal

Journal of labelled compounds & radiopharmaceuticals
ISSN: 1099-1344
Titre abrégé: J Labelled Comp Radiopharm
Pays: England
ID NLM: 7610510

Informations de publication

Date de publication:
04 2019
Historique:
received: 25 08 2018
revised: 14 12 2018
accepted: 10 01 2019
pubmed: 22 1 2019
medline: 14 4 2020
entrez: 22 1 2019
Statut: ppublish

Résumé

In spite of previous efforts, there is lack of a radiotracer for imaging the 5HT

Identifiants

DOI: 10.1002/jlcr.3709 PMID: 30663099
pubmed: 30663099
doi: 10.1002/jlcr.3709
doi:

Substances chimiques

HTR2C protein, human 0
Organotechnetium Compounds 0
Receptor, Serotonin, 5-HT2C 0
Piperazine 1RTM4PAL0V

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

166-177

Informations de copyright

© 2019 John Wiley & Sons, Ltd.

Auteurs

Mostafa Erfani (M)

Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran.
ORCID: 0000-0002-5674-1575

Hadi Malek (H)

Department of Nuclear Medicine and Molecular Imaging, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Seyed Esmaeil Sadat Ebrahimi (SE)

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Leila Hassanzadeh (L)

Department of Nuclear Medicine, School of Medicine, Rajaie Cardiovascular, Medical & Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Medicinal Chemistry, School of Pharmacy-International Campus, Iran University of Medical Sciences, Tehran, Iran.
ORCID: 0000-0001-8958-8848

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › New
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › New
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Technologie pharmaceutique › Techniques de chimie synthétique › Chimie click › New
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › New
questionsmedicales.fr › Techniques d'investigation › Marquage isotopique › New
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › New
questionsmedicales.fr › Composés chimiques organiques › Composés organométalliques › Composés organiques du technétium › New
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pipérazines › Pipérazine › New
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › New
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Chimie physique › Radiochimie › New
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › New
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs sérotoninergiques › Récepteurs de la sérotonine de type 5-HT2 › Récepteur de la sérotonine de type 5-HT2C › New
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Distribution tissulaire › New