Engineering of a bioluminescent probe for imaging nitroxyl in live cells and mice.

Animals Cell Line, Tumor Fluorescent Dyes / chemistry Humans Luminescent Measurements Mice Neoplasms / diagnostic imaging Nitrogen Oxides / chemistry Optical Imaging Transfection Transplantation, Heterologous

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
05 Feb 2019
Historique:
pubmed: 22 1 2019
medline: 15 2 2019
entrez: 22 1 2019
Statut: ppublish

Résumé

A bioluminescent probe, BP-HNO, which exhibits a turn-on response to nitroxyl with high sensitivity and selectivity, is reported for the first time in this work. BP-HNO is free from the interference of biological autofluorescence to afford a high signal-to-noise ratio for bioimaging, and was successfully applied to imaging nitroxyl in live cells and mice.

Identifiants

DOI: 10.1039/c9cc00211a PMID: 30664144
pubmed: 30664144
doi: 10.1039/c9cc00211a
doi:

Substances chimiques

Fluorescent Dyes 0
Nitrogen Oxides 0
nitroxyl GFQ4MMS07W

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1758-1761

Auteurs

Jun-Bin Li (JB)

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Life Sciences, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn.

Qianqian Wang (Q)

Hong-Wen Liu (HW)

Xia Yin (X)

Xiao-Xiao Hu (XX)

Lin Yuan (L)

Xiao-Bing Zhang (XB)

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Photométrie › Mesures de luminescence › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Tumeurs › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Techniques d'investigation › Imagerie optique › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Phénomènes génétiques › Recombinaison génétique › Transfection › Engineering of a bioluminescent probe for...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation hétérologue › Engineering of a bioluminescent probe for...