Neural Coding of Contact Events in Somatosensory Cortex.
neural coding
object manipulation
population coding
tactile fiber
touch
Journal
Cerebral cortex (New York, N.Y. : 1991)
ISSN: 1460-2199
Titre abrégé: Cereb Cortex
Pays: United States
ID NLM: 9110718
Informations de publication
Date de publication:
17 12 2019
17 12 2019
Historique:
received:
10
05
2018
revised:
07
12
2018
accepted:
17
12
2018
pubmed:
23
1
2019
medline:
21
10
2020
entrez:
23
1
2019
Statut:
ppublish
Résumé
Manual interactions with objects require precise and rapid feedback about contact events. These tactile signals are integrated with motor plans throughout the neuraxis to achieve dexterous object manipulation. To better understand the role of somatosensory cortex in interactions with objects, we measured, using chronically implanted arrays of electrodes, the responses of populations of somatosensory neurons to skin indentations designed to simulate the initiation, maintenance, and termination of contact with an object. First, we find that the responses of somatosensory neurons to contact onset and offset dwarf their responses to maintenance of contact. Second, we show that these responses rapidly and reliably encode features of the simulated contact events-their timing, location, and strength-and can account for the animals' performance in an amplitude discrimination task. Third, we demonstrate that the spatiotemporal dynamics of the population response in cortex mirror those of the population response in the nerves. We conclude that the responses of populations of somatosensory neurons are well suited to encode contact transients and are consistent with a role of somatosensory cortex in signaling transitions between task subgoals.
Identifiants
pubmed: 30668644
pii: 5298364
doi: 10.1093/cercor/bhy337
pmc: PMC6917522
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
4613-4627Subventions
Organisme : NINDS NIH HHS
ID : R01 NS095251
Pays : United States
Organisme : NINDS NIH HHS
ID : F31 NS096952
Pays : United States
Informations de copyright
© The Author(s) 2019. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
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