Total Reference Air Kerma is Associated with Late Bowel Morbidity in Locally Advanced Cervical Cancer Patients Treated with Image-Guided Adaptive Brachytherapy.
bowel
cervical cancer
dose-volume parameters
image-guided adaptive brachytherapy
morbidity
normal tissue complication probability
sigmoid
total reference air kerma
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
21 Jan 2019
21 Jan 2019
Historique:
received:
22
12
2018
revised:
12
01
2019
accepted:
16
01
2019
entrez:
24
1
2019
pubmed:
24
1
2019
medline:
24
1
2019
Statut:
epublish
Résumé
No dose volume parameter has been identified to predict late bowel toxicities in locally advanced cervical cancer (LACC) patients treated with image-guided adaptive brachytherapy. We examined the incidence of bowel toxicities according to the total reference air kerma (TRAK) in 260 LACC patients. In both univariate and multivariate analysis, late morbidity positively correlated with a TRAK ≥2 cGy (centigray) at 1 meter, emphasizing the importance of this parameter in term of late bowel morbidity.
Identifiants
pubmed: 30669569
pii: jcm8010125
doi: 10.3390/jcm8010125
pmc: PMC6352249
pii:
doi:
Types de publication
Journal Article
Langues
eng
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